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Titolo:
MUSCARINIC ANTAGONIST ACTIVITY OF (5-ALKOXY-OXAZOL-2-YL)-1,2,5,6-TETRAHYDROPYRIDINES
Autore:
MITCH CH; BYMASTER FP; CALLIGARO DO; QUIMBY SJ; SCHOEPP DD; WONG DT; SHANNON HE;
Indirizzi:
ELI LILLY & CO,LILLY CORP CTR,LILLY RES LABS,CNS GI GU RES INDIANAPOLIS IN 46285
Titolo Testata:
Bioorganic & medicinal chemistry letters
fascicolo: 14, volume: 4, anno: 1994,
pagine: 1721 - 1724
SICI:
0960-894X(1994)4:14<1721:MAAO(>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTORS; DERIVATIVES; ARECOLINE; AGONISTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
C.H. Mitch et al., "MUSCARINIC ANTAGONIST ACTIVITY OF (5-ALKOXY-OXAZOL-2-YL)-1,2,5,6-TETRAHYDROPYRIDINES", Bioorganic & medicinal chemistry letters, 4(14), 1994, pp. 1721-1724

Abstract

A series of (5-alkoxy-oxazol-2-yl)-1,2,5,6-tetrahydropyridines (OXTP)were found to have high affinity for muscarinic receptors and to be potent muscarinic antagonists as measured by blockade of acetylcholine stimulated PI hydrolysis in rat cortex or by blockade of oxotremorine induced tremors in mice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 12:10:51