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Titolo:
THE GENOMIC STRUCTURE ENCODING HUMAN INITIATION-FACTOR EIF-5A
Autore:
KOETTNITZ K; KAPPEL B; BAUMRUKER T; HAUBER J; BEVEC D;
Indirizzi:
SANDOZ GMBH,RES INST,BRUNNER STR 59 A-1235 VIENNA AUSTRIA SANDOZ GMBH,RES INST A-1235 VIENNA AUSTRIA
Titolo Testata:
Gene
fascicolo: 2, volume: 144, anno: 1994,
pagine: 249 - 252
SICI:
0378-1119(1994)144:2<249:TGSEHI>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPUSINE; ACTIVATION; MECHANISM; PROTEIN;
Keywords:
COSMID CLONES; SINGLE-EXON CODING REGION; PSEUDOGENES; HIV-1;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
K. Koettnitz et al., "THE GENOMIC STRUCTURE ENCODING HUMAN INITIATION-FACTOR EIF-5A", Gene, 144(2), 1994, pp. 249-252

Abstract

A genomic clone encoding the human eukaryotic initiation factor 5A (eIF-5A) was isolated and its entire nucleotide sequence was determined. The whole eIF-5A coding region is not interrupted by introns. The functional eIF-5A gene is highly homologous to the corresponding complementary DNA. One single 1.4-kb transcript thereof is expressed in human cell lines. Furthermore, we also isolated and sequenced two additonal eIF-5A-related sequences which are, by expression and sequence analyses, identified as pseudogenes of the functional eIF-5A. The sequence homology between these pseudogenes and the functional eIF-5A is 71 and 87%.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 23:08:42