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Titolo:
PLASMA SEROTONIN INCREASE DURING EPISODES OF TENSION-TYPE HEADACHE
Autore:
JENSEN R; HINDBERG I;
Indirizzi:
GENTOFTE UNIV HOSP,DEPT NEUROL DK-2900 COPENHAGEN DENMARK FREDERICKSBERG HOSP,DEPT CLIN CHEM FREDERIKSBERG DENMARK
Titolo Testata:
Cephalalgia
fascicolo: 3, volume: 14, anno: 1994,
pagine: 219 - 222
SICI:
0333-1024(1994)14:3<219:PSIDEO>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
MUSCLE-CONTRACTION HEADACHE; PLATELET ACTIVATION; MIGRAINE; 5-HYDROXYTRYPTAMINE;
Keywords:
PLATELET-POOR PLASMA; SEROTONIN; TENSION-TYPE HEADACHE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
R. Jensen e I. Hindberg, "PLASMA SEROTONIN INCREASE DURING EPISODES OF TENSION-TYPE HEADACHE", Cephalalgia, 14(3), 1994, pp. 219-222

Abstract

The mechanisms of tension-type headache remain to be determined. Biochemical abnormalities have been rarely demonstrated. We performed a controlled study of 5-hydroxytryptamine (5HT) in platelet poor plasma obtained from 13 female patients during and between episodes of tension-type headache. The 5HT concentration in patients free of headache was not different from controls, whereas a significant increase in 5HT concentration was seen during headache (p < 0.02). This finding is attributed to release of 5HT from platelets or disordered 5HT metabolism during headache attacks, possibly related to pain in the latter case. We conclude that 5HT may be involved in the pathogenesis of tension-type headache but by different mechanisms than migraine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 22:56:06