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Titolo:
PROCALCITONIN AND C-REACTIVE PROTEIN-LEVELS IN NEONATAL INFECTIONS
Autore:
MONNERET G; LABAUNE JM; ISAAC C; BIENVENU F; PUTET G; BIENVENU J;
Indirizzi:
CTR HOSP LYON SUD,IMMUNOL LAB F-69495 PIERRE BENITE FRANCE CTR HOSP LYON SUD,IMMUNOL LAB F-69495 PIERRE BENITE FRANCE HOP DEBROUSSE,BIOCHIM LAB LYON FRANCE
Titolo Testata:
Acta paediatrica
fascicolo: 2, volume: 86, anno: 1997,
pagine: 209 - 212
SICI:
0803-5253(1997)86:2<209:PACPIN>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEPSIS; INTERLEUKIN-6;
Keywords:
C-REACTIVE PROTEIN; NEONATAL INFECTION; PROCALCITONIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
G. Monneret et al., "PROCALCITONIN AND C-REACTIVE PROTEIN-LEVELS IN NEONATAL INFECTIONS", Acta paediatrica, 86(2), 1997, pp. 209-212

Abstract

In order to assess the potential of procalcitonin measurement in the management of neonatal sepsis, daily variations in serum procalcitonin(measured by an immunoluminometric assay) were evaluated in 94 control and infected newborn infants in comparison to C-reactive protein (measured by an immunonephelometric method). High levels of procalcitonincorrelated with bacterial invasion and showed no discrepancies with C-reactive protein. Procalcitonin increased (up to 400 mu g l(-1)) and returned to the normal range (< 0.1 mu g l(-1)) more quickly than C-reactive protein, suggesting that procalcitonin may be an early marker of favourable outcome. Another finding is a significant procalcitonin peak on the first day of life in the control group, independent of any infectious stimulus. In conclusion, procalcitonin seems to be an interesting marker of neonatal sepsis but additional investigations are needed to understand better its mechanism of synthesis in order to determine its clinical usefulness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 04:30:54