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Titolo:
EFFECTS OF POSTNATAL BLOCKADE OF CORTICAL ACTIVITY WITH TETRODOTOXIN UPON LESION-INDUCED REORGANIZATION OF VIBRISSAE-RELATED PATTERNS IN THE SOMATOSENSORY CORTEX OF RAT
Autore:
CHIAIA NL; FISH SE; BAUER WR; FIGLEY BA; ECK M; BENNETTCLARKE CA; RHOADES RW;
Indirizzi:
MED COLL OHIO,DEPT ANAT,CS 10008 TOLEDO OH 43699 MARSHALL UNIV,SCH MED,DEPT ANAT HUNTINGTON WV 25704
Titolo Testata:
Developmental brain research
fascicolo: 2, volume: 79, anno: 1994,
pagine: 301 - 306
SICI:
0165-3806(1994)79:2<301:EOPBOC>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
BINOCULAR IMPULSE BLOCKADE; KITTEN VISUAL-CORTEX; SEROTONIN; INFUSION; DISRUPT;
Keywords:
BARREL; NEURONAL ACTIVITY; TETRODOTOXIN; TRIGEMINAL SYSTEM; DI-I; SEROTONIN;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
N.L. Chiaia et al., "EFFECTS OF POSTNATAL BLOCKADE OF CORTICAL ACTIVITY WITH TETRODOTOXIN UPON LESION-INDUCED REORGANIZATION OF VIBRISSAE-RELATED PATTERNS IN THE SOMATOSENSORY CORTEX OF RAT", Developmental brain research, 79(2), 1994, pp. 301-306

Abstract

Previous studies have shown that postnatal blockade of thalamocortical activity with either tetrodotoxin (TTX) or the NMDA receptor antagonist DL-2-amino-5-phosphonovalerate (APV) does not prevent the formation of vibrissae-related patterns. In the present study, blockade of cortical activity with TTX was combined with ablation of a row of vibrissae follicles or transection of the infraorbital nerve (ION, the trigeminal nerve branch that supplies the vibrissae follicles) to determine whether the cortical reorganization that follows these lesions in otherwise untreated animals was dependent upon neuronal activity that could be blocked with TTX. The results demonstrated that cortical TTX implants had no quantitative or qualitative effects upon the cortical reorganization that followed either vibrissae follicle cauterization or ION transection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 05:24:58