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Titolo:
THYMIC CARCINOMA - PROPOSAL FOR PATHOLOGICAL TNM AND STAGING
Autore:
TSUCHIYA R; KOGA K;
Indirizzi:
NATL CANC CTR,DIV THORAC SURG,CHUO KU,5-1-1 TSUKIJI TOKYO 104 JAPAN NATL CANC CTR,DIV CLIN LABS TOKYO JAPAN NATL CANC CTR,DIV PATHOL TOKYO JAPAN RES INST TOKYO JAPAN FUKUOKA UNIV,DEPT INTERNAL MED FUKUOKA 81401 JAPAN
Titolo Testata:
Pathology international
fascicolo: 7, volume: 44, anno: 1994,
pagine: 505 - 512
SICI:
1320-5463(1994)44:7<505:TC-PFP>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPSTEIN-BARR-VIRUS; THYMOMAS;
Keywords:
PROGNOSIS; STAGING; THYMIC CARCINOMA; THYMUS; TNM CLASSIFICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
R. Tsuchiya e K. Koga, "THYMIC CARCINOMA - PROPOSAL FOR PATHOLOGICAL TNM AND STAGING", Pathology international, 44(7), 1994, pp. 505-512

Abstract

Recently, Yamakawa ef al. following Masaoka's clinical staging of thymic epithelial tumors, proposed a TNM classification and staging system for thymic epithelial tumors including thymoma and thymic carcinoma. The present authors consider that division of thymomas into circumscribed types (either encapsulated or non-encapsulated but confined to within the thymus) and those invasive to adjacent organs or structures is sufficiently practical, and that a staging system is applicable to thymic carcinoma, carcinoid tumors and germ cell tumors of the anteriormediastinum, which are more malignant than thymoma. Therefore, the utility of the Yamakawa/Masaoka TNM and staging system was evaluated anda modification proposed based on experience with 16 thymic carcinomas. Although there were no cases at stage II, the survival curves obtained using the proposed modified system were more clearly separated between stages I and III or IV and between stages III and IV than the curves obtained using the Yamakawa/Masaoka system. However, the differences were not significant because of the small number of cases included, A statistically significant difference was noted between the survival curves for patients who underwent complete and incomplete surgical resection of the tumor. The utility of this proposed TNM and staging system must be evaluated by other investigators, since no cases of small cell carcinoma, lymphoepithelioma-like carcinoma, sarcomatoid carcinomaand clear cell carcinoma were included in this series, all of which are considered to have high-grade histology. An evaluation of carcinoidtumor and germ cell tumor of the anterior mediastinum must also be made.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 19:32:17