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Titolo:
HEPATIC VENOOCCLUSIVE DISEASE-ASSOCIATED TO THE USE OF AZATHIOPRINE IN A RENAL-TRANSPLANT RECIPIENT
Autore:
HOLA K; BRAHM J; ALVO M; COTERA A; PASSALACQUA W; SMOK G;
Indirizzi:
UNIV CHILE,HOSP CLIN,CTR GASTROENTEROL,SECC NEFROL,DEPT MED INTERNA,SANTOS DUMONT 999 SANTIAGO CHILE UNIV CHILE,HOSP CLIN,CTR GASTROENTEROL,SECC NEFROL,DEPT MED INTERNA SANTIAGO CHILE UNIV CHILE,HOSP CLIN,CTR GASTROENTEROL,DEPT ANAT PATOL SANTIAGO CHILE
Titolo Testata:
Revista Medica de Chile
fascicolo: 12, volume: 124, anno: 1996,
pagine: 1489 - 1491
SICI:
0034-9887(1996)124:12<1489:HVDTTU>2.0.ZU;2-2
Fonte:
ISI
Lingua:
SPA
Soggetto:
LIVER-TRANSPLANTATION; INJURY;
Keywords:
THROMBOPHLEBITIS; VENOOCCLUSIVE DISEASE; HEPATITIS, TOXIC; AZATHIOPRINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
K. Hola et al., "HEPATIC VENOOCCLUSIVE DISEASE-ASSOCIATED TO THE USE OF AZATHIOPRINE IN A RENAL-TRANSPLANT RECIPIENT", Revista Medica de Chile, 124(12), 1996, pp. 1489-1491

Abstract

We report a 30 years old male, recipient of a kidney allograft and treated with azathioprine, who eighteen days after transplantation had aclinically asymptomatic elevation of total bilirubin and alkaline phosphatases. Nineteen months later, he presented with mild ascites, witha total bilirubin of 3.5 mg/dl, alkaline phosphatases of 308 U/L (normal <170 U/L) and a prothrombin time at 55% of control. A liver biopsyshowed sinusoidal and perivenular fibrosis without inflammation, compatible with chronic venous obstruction. Hepatic veno-occlusive diseaseis an infrequent complication of azathioprine use.

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Documento generato il 22/02/20 alle ore 21:31:36