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Titolo:
ATTENTION-DEFICIT HYPERACTIVITY DISORDER - MAGNETIC-RESONANCE-IMAGINGMORPHOMETRIC ANALYSIS OF THE CORPUS-CALLOSUM
Autore:
SEMRUDCLIKEMAN M; FILIPEK PA; BIEDERMAN J; STEINGARD R; KENNEDY D; RENSHAW P; BEKKEN K;
Indirizzi:
UNIV WASHINGTON,322 MILLER HALL,DQ-12 SEATTLE WA 98195 CHILDRENS HOSP MED CTR,DEPT PSYCHIAT BOSTON MA 02115 MCLEAN HOSP,NEUROIMAGING UNIT BELMONT MA 02178 HARVARD UNIV,MASSACHUSETTS GEN HOSP,SCH MED,CTR MORPHOMETR ANAL BOSTON MA 02114 MASSACHUSETTS GEN HOSP,DEPT NEUROL,NEUROPSYCHOL LAB BOSTON MA 02114 MASSACHUSETTS GEN HOSP,PEDIAT PSYCHOPHARMACOL UNIT BOSTON MA 02114
Titolo Testata:
Journal of the American Academy of Child and Adolescent Psychiatry
fascicolo: 6, volume: 33, anno: 1994,
pagine: 875 - 881
SICI:
0890-8567(1994)33:6<875:AHD-M>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEVELOPMENTAL DYSLEXIA; SUSTAINED ATTENTION; CHILDREN; BRAIN; MORPHOLOGY; CHILDHOOD; ADULTS; MRI;
Keywords:
ATTENTION-DEFICIT HYPERACTIVITY DISORDER; CORPUS CALLOSUM; MAGNETIC RESONANCE IMAGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
M. Semrudclikeman et al., "ATTENTION-DEFICIT HYPERACTIVITY DISORDER - MAGNETIC-RESONANCE-IMAGINGMORPHOMETRIC ANALYSIS OF THE CORPUS-CALLOSUM", Journal of the American Academy of Child and Adolescent Psychiatry, 33(6), 1994, pp. 875-881

Abstract

Objective: The following study seeks to document possible differencesin corpus callosal area and shape between children with attention-deficit hyperactivity disorder (ADHD) and controls. Method: Fifteen carefully diagnosed right-handed male subjects with ADHD with overactivity symptomatology were compared to 15 right-handed male control subjects. The corpus callosum was divided into seven areas on the midsagittal slice of a magnetic resonance image with shape analysis also conducted. Results: An exploratory shape analysis showed no significant differences in shape between the groups. No group differences were found in the area, length, or anterior regions of the corpus callosum. The ADHD subjects were found to have significantly smaller posterior corpus callosum regions than the control group, with the splenium accounting for most of the variance between the groups. Conclusions: The splenial area ot the corpus callosum is smaller in children with ADHD than in a sample of normally developing children. These smaller areas may relate to commonly seen sustained attention deficits which in turn negatively impact on the development of more advanced levels of attention such asself-regulation. Further study of the regions surrounding the splenial area is suggested to determine whether they are correlated in size to the smaller corpus callosum.

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Documento generato il 05/12/20 alle ore 13:18:12