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Titolo:
CAUSES OF THE INCREASED STROKE RATE AFTER CAROTID ENDARTERECTOMY IN PATIENTS WITH PREVIOUS STROKES
Autore:
ROCKMAN CB; CAPPADONA C; RILES TS; LAMPARELLO PJ; GIANGOLA G; ADELMAN MA; LANDIS R;
Indirizzi:
NYU,MED CTR,DEPT SURG,DIV VASC SURG,530 1ST AVE,SUITE 6F NEW YORK NY 10016 NYU,MED CTR,DEPT SURG,DIV VASC SURG NEW YORK NY 10016
Titolo Testata:
Annals of vascular surgery
fascicolo: 1, volume: 11, anno: 1997,
pagine: 28 - 34
SICI:
0890-5096(1997)11:1<28:COTISR>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLOGIC COMPLICATIONS; ARTERY; IMMEDIATE; SURVIVAL; SURGERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
C.B. Rockman et al., "CAUSES OF THE INCREASED STROKE RATE AFTER CAROTID ENDARTERECTOMY IN PATIENTS WITH PREVIOUS STROKES", Annals of vascular surgery, 11(1), 1997, pp. 28-34

Abstract

Patients who have sustained a preoperative stroke are at increased risk for perioperative stroke after carotid endarterectomy. At our institution this risk was recently shown to be increased two-to threefold. The purpose of this study was to investigate the reasons for the increased surgical risk in these patients. Records of 606 patients undergoing 704 consecutive carotid endarterectomies from 1988 through 1993 were reviewed. Patients who suffered preoperative strokes (n = 183) were compared to those who were either asymptomatic or experienced only transient ischemic attacks (TIAs) preoperatively (n = 423). Of the 183 patients who had suffered preoperative strokes, eight patients who experienced perioperative strokes after endarterectomy were compared with 175 who successfully underwent surgery. Patients with a prior stroke had an increased perioperative stroke rate (4.4% versus 1.2%, p = 0.01). They had a significantly higher incidence of hypertension (62.6% versus 47.9%, p < 0.001), cardiac disease (54.7% versus 40.7%, p = 0.001),and positive smoking history (52% versus 40.6%, p = 0.01) than did the asymptomatic/TIA patients. The presence of contralateral total occlusion was also significantly increased (22% versus 10.3%, p < 0.001). Although not statistically significant due to the overall small number of patients who sustained perioperative strokes, the preoperative stroke patients who sustained perioperative strokes had a higher incidenceof hypertension (87.5% versus 61.5%) and contralateral total occlusion (37.5% versus 21.3%) than did those who successfully underwent surgery. Patients with both a prior stroke and contralateral total occlusion had a 7.5% perioperative stroke rate. Patients with both a prior stroke and hypertension had a 6.1% perioperative stroke rate. The perioperative strokes in patients with prior strokes were not related to the severity of the prior stroke, the interval between the stroke and surgery, the use of a shunt, or the type of anesthesia employed. Patients who have sustained preoperative strokes have a higher incidence of significant medical illnesses and overall cerebrovascular disease. Hypertension and total occlusion of the contralateral carotid artery appear to be particularly poor prognostic indicators of outcome after endarterectomy in these patients. Patients who have sustained preoperative strokes may be more likely to display clinical neurologic symptoms in response to any form of cerebral ischemia. In this higher risk subgroup,intraoperative and surgeon-dependent factors appear to play less of arole.

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Documento generato il 22/10/20 alle ore 12:39:26