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Titolo:
PHARMACEUTICAL APPLICATIONS OF MICROCALORIMETRY
Autore:
KOENIGBAUER MJ;
Indirizzi:
ZENECA INC,PHARMACEUT GRP,BUSINESS UNIT,1800 CONCORD PIKE WILMINGTON DE 19897
Titolo Testata:
Pharmaceutical research
fascicolo: 6, volume: 11, anno: 1994,
pagine: 777 - 783
SICI:
0724-8741(1994)11:6<777:PAOM>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEAT-CONDUCTION MICROCALORIMETRY; T-LYMPHOMA CELLS; CONTROLLED RELEASE PREPARATIONS; SOLID-STATE STABILITY; ISOTHERMAL CALORIMETRY; FLOW MICROCALORIMETRY; ARTIFICIAL FOODSTUFFS; ANTINEOPLASTIC DRUGS; MICRO-CALORIMETRY; AQUEOUS-SOLUTION;
Keywords:
DRUG STABILITY; DEGRADATION RATE; CALORIMETRY; DRUG INTERACTIONS; EXCIPIENT INTERACTIONS; MICROCALORIMETRY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
M.J. Koenigbauer, "PHARMACEUTICAL APPLICATIONS OF MICROCALORIMETRY", Pharmaceutical research, 11(6), 1994, pp. 777-783

Abstract

General principles and applications of microcalorimetry are reviewed. Microcalorimetry is useful in the study of physical, chemical, and biological drug interactions. The sensitivity of the present instrumentation is approximately 0.1 mu W. With this high sensitivity, additionalapplications have been developed, including the interactions of drugswith food, lymphoma cells, microorganisms, blood, excipients, and cyclodextrin. A recent application of: microcalorimetry is the measurement of degradation rates of drugs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 08:58:34