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Titolo:
AN ANALYSIS OF THE SEQUENCE OF PART OF THE RIGHT ARM OF CHROMOSOME-IIOF SACCHAROMYCES-CEREVISIAE REVEALS NEW GENES ENCODING AN AMINO-ACID PERMEASE AND A CARBOXYPEPTIDASE
Autore:
NASR F; BECAM AM; GRZYBOWSKA E; ZAGULSKI M; SLONIMSKI PP; HERBERT CJ;
Indirizzi:
UNIV PIERRE & MARIE CURIE,CTR GENET MOLEC,CNRS,PROPRE LAB F-91198 GIFSUR YVETTE FRANCE UNIV PIERRE & MARIE CURIE,CTR GENET MOLEC,CNRS,PROPRE LAB F-91198 GIFSUR YVETTE FRANCE POLISH ACAD SCI,INST BIOCHEM & BIOPHYS WARSAW POLAND
Titolo Testata:
Current genetics
fascicolo: 1, volume: 26, anno: 1994,
pagine: 1 - 7
SICI:
0172-8083(1994)26:1<1:AAOTSO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEMBRANE-SPANNING PROTEINS; LYSINE-SPECIFIC PERMEASE; SACCHAROMYCES-CEREVISIAE; NUCLEOTIDE-SEQUENCE; YEAST; PROPEPTIDE; DNA; CLASSIFICATION; SIMILARITY; ALIGNMENT;
Keywords:
YEAST; SEQUENCE; AMINO-ACID PERMEASE; CARBOXYPEPTIDASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
F. Nasr et al., "AN ANALYSIS OF THE SEQUENCE OF PART OF THE RIGHT ARM OF CHROMOSOME-IIOF SACCHAROMYCES-CEREVISIAE REVEALS NEW GENES ENCODING AN AMINO-ACID PERMEASE AND A CARBOXYPEPTIDASE", Current genetics, 26(1), 1994, pp. 1-7

Abstract

We have analysed two new genes, YBR1007 and YBR1015, discovered during the systematic sequencing of chromosome II of S. cerevisiae. YBR1007shows strong similarities to amino-acid permeases, in particular the high-affinity proline permeases of S. cerevisiae and A. nidulans. The number and position of the predicted membrane-spanning domains suggesta conserved structure for these proteins, with 12 trans-membrane domains. YBR1015 shows strong similarities to serine carboxypeptidases; all three residues of the ''catalytic triad'' typical bf this family of enzymes are conserved in the YBR1O15 protein. In a preliminary functional analysis we have created a null allele of the YBR1015 gene, and shown that it is not essential for cellular viability.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:59:34