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Titolo:
SURGERY OF PHEOCHROMOCYTOMA - 12-YEAR DEV ELOPMENT
Autore:
KOCHER T; VONFLUE M; ZUBER M; STAUB JJ; SCHEIDEGGER D; HARDER F;
Indirizzi:
KANTONSSPITAL,DEPT CHIRURG CH-4031 BASEL SWITZERLAND KANTONSSPITAL BASEL,DEPT INNERE MED,ENDOKRINOL ABT BASEL SWITZERLAND KANTONSSPITAL BASEL,DEPT ANASTHESIE BASEL SWITZERLAND
Titolo Testata:
Schweizerische medizinische Wochenschrift
fascicolo: 22, volume: 124, anno: 1994,
pagine: 953 - 956
SICI:
0036-7672(1994)124:22<953:SOP-1D>2.0.ZU;2-P
Fonte:
ISI
Lingua:
GER
Soggetto:
LOCALIZATION; DIAGNOSIS; MANAGEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
T. Kocher et al., "SURGERY OF PHEOCHROMOCYTOMA - 12-YEAR DEV ELOPMENT", Schweizerische medizinische Wochenschrift, 124(22), 1994, pp. 953-956

Abstract

Hypertension (sustained and/or paroxysmal) is the most common symptomof pheochromocytoma. Correct evaluation nearly always leads to the diagnosis, and complete surgical excision is the definitive treatment. Our study deals with preoperative evaluation, operative morbidity and long-term results after surgery. During the 12-year period (1981-1992) 31 patients (48 years, 25-85) with pheochromocytoma were treated at our institution. The selected preoperative management was reviewed on the basis of patient records. Longterm follow-up was carried out consecutively and personally. All patients received alpha-adrenergic blockersto achieve preoperative normotension and volume repletion. All resections were performed by laparotomy; two of the early cases were extended into the chest. 27 of 29 patients (93.1%) had elevated levels of urinary vanillylmandelic acid; a similar sensitivity was noted in the urinary catecholamines (24/26 = 92.3%). In anatomical localization CT-scan was accurate in 100% (27/27). MIGB scintigraphy was of help in 21 of23 (91.3%) and, in the most recent patients, MRI was helpful in 3 of 3 (100%). No patient died during the first 30 days after surgery. One patient developed an anaphylactic reaction after cephalosporin administration (morbidity: 3.2%). 2 patients (6.4%) with malignant pheochromocytoma developed a recurrent tumor during the follow-up period. Resection of pheochromocytomas by laparotomy has a low perioperative morbidity and mortality after standardized preparation. A positive MIBG scintigraphy allows extraadrenal localization. Better resolution and multiplanar imaging are the advantages of MRI. Perioperative management and new imaging techniques - eliminating arteriography and venous samplingamong others - have simplified surgical treatment and improved its safety.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 20:24:23