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Titolo:
A PILOT-STUDY OF LEAD AND CADMIUM EXPOSURE IN YOUNG-CHILDREN IN STOCKHOLM, SWEDEN - METHODOLOGICAL CONSIDERATIONS USING CAPILLARY BLOOD MICROSAMPLING
Autore:
BERGLUND M; LIND B; LANNERO E; VAHTER M;
Indirizzi:
KAROLINSKA INST,INST ENVIRONM MED,BOX 210 S-17177 STOCKHOLM SWEDEN KRONAN PRIMARY HLTH CARE CTR S-17231 SUNDBYBERG SWEDEN
Titolo Testata:
Archives of environmental contamination and toxicology
fascicolo: 2, volume: 27, anno: 1994,
pagine: 281 - 287
SICI:
0090-4341(1994)27:2<281:APOLAC>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PORT-PIRIE COHORT; AGE 5 YEARS; COGNITIVE-DEVELOPMENT; ENVIRONMENTAL EXPOSURE; PRESCHOOL-CHILDREN; CINCINNATI LEAD; SOIL; ABSORPTION; SWEDISH; INTELLIGENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
M. Berglund et al., "A PILOT-STUDY OF LEAD AND CADMIUM EXPOSURE IN YOUNG-CHILDREN IN STOCKHOLM, SWEDEN - METHODOLOGICAL CONSIDERATIONS USING CAPILLARY BLOOD MICROSAMPLING", Archives of environmental contamination and toxicology, 27(2), 1994, pp. 281-287

Abstract

A capillary blood microsampling technique was tested among urban young children in Stockholm. Blood lead (BPb) and hemoglobin (Hb) concentrations were determined in capillary blood obtained by fingerstick from41 children, 13-20 months old, and the accompanying parent. The quality control included control for lead (Pb) and cadmium (Cd) contamination of material and equipment used for blood sampling, washing procedures for the hands and fingers to be punctured, comparisons of Pb and Cdconcentrations in blood obtained by finger-stick and by brachial veinpuncture from the same individuals, analysis of external quality control samples for Pb and Cd in blood together with the collected samples, and evaluation of the analytical performance using linear regressionanalysis. The results showed that blood sampling material may contaminate the blood samples with amounts of Pb and Cd that would seriously influence the monitoring results in the low concentration range (< 100mug Pb/L and < 1 mug Cd/L). However, it is possible to obtain reliable BPb concentrations (> 10 mug Pb/L), but not BCd concentrations (< 1 mug Cd/L), with the capillary blood microsampling technique tested provided that a strict quality control is applied. The sampling proceduretested was well accepted by the children and their parents. The children's median BPb concentration (27 mug/L; range 9-73 mug/L) was similar to the median BPb concentration of their parents (27 mug/L; range 7-74 mug/L). However, the correlation between child and parent BPb concentrations was poor (R2 = 0.20), which may indicate different source s to Pb exposure in children and parents.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 19:17:44