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Titolo:
SEASONAL REGULATION OF MELATONIN RECEPTORS IN RODENT PARS TUBERALIS -CORRELATION WITH REPRODUCTIVE STATE
Autore:
GAUER F; MASSONPEVET M; PEVET P;
Indirizzi:
UNIV STRASBOURG 1,CNRS,URA 1332,12 RUE UNIV F-67000 STRASBOURG FRANCE UNIV STRASBOURG 1,CNRS,URA 1332 F-67000 STRASBOURG FRANCE
Titolo Testata:
Journal of neural transmission
fascicolo: 3, volume: 96, anno: 1994,
pagine: 187 - 195
SICI:
0300-9564(1994)96:3<187:SROMRI>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
BINDING-SITES; PINEAL-GLAND; HAMSTERS; AUTORADIOGRAPHY; PITUITARY; SIGNAL; BRAIN;
Keywords:
MELATONIN RECEPTORS; SEASONAL VARIATION; PHOTOPERIOD; PARS TUBERALIS; REPRODUCTIVE STATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
F. Gauer et al., "SEASONAL REGULATION OF MELATONIN RECEPTORS IN RODENT PARS TUBERALIS -CORRELATION WITH REPRODUCTIVE STATE", Journal of neural transmission, 96(3), 1994, pp. 187-195

Abstract

Using quantitative autoradiography, we have studied the relationship between melatonin receptor density in the pars tuberalis (PT) and photoperiodic changes in sexual activity in a photoperiodic (Syrian hamster), and a non photoperiodic (rat) rodent. Syrian hamsters exposed to short photoperiod (SP) for 13 weeks or kept in long photoperiod (LP) with daily melatonin injections for 8 weeks, had both gonadal regressionand a significant decrease in 2-I-125- melatonin binding site densityin the PT when compared to controls. In contrast, when the animals were sexually active, photorefractory Syrian hamsters exposed to SP for 27 weeks, or rats kept for 13 weeks in SP, the PT melatonin receptor density was similar to that of control animals kept in LP. These results show clearly that a correlation exists between gonadal status and density of melatonin receptors in the PT and suggest that the PT could be the site where melatonin mediates its effects on seasonal function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 12:49:38