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Titolo:
PRECURSORS OF EXTRACRANIAL CAROTID ATHEROSCLEROSIS IN THE FRAMINGHAM-STUDY
Autore:
FINEEDELSTEIN JS; WOLF PA; OLEARY DH; POEHLMAN H; BELANGER AJ; KASE CS; DAGOSTINO RB;
Indirizzi:
ROBINSON BLDG B-608,80 E CONCORD ST BOSTON MA 02118 BOSTON UNIV,SCH MED,DEPT NEUROL BOSTON MA 02118 BOSTON UNIV,DEPT MATH BOSTON MA 02215 GEISINGER MED CLIN,DIV RADIOL DANVILLE PA 00000 FRAMINGHAM HEART DIS EPIDEMIOL STUDY FRAMINGHAM MA 00000
Titolo Testata:
Neurology
fascicolo: 6, volume: 44, anno: 1994,
pagine: 1046 - 1050
SICI:
0028-3878(1994)44:6<1046:POECAI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
B-MODE ULTRASOUND; RISK-FACTORS; ARTERY ATHEROSCLEROSIS; CIGARETTE-SMOKING; CARDIOVASCULAR-DISEASE; SERUM-LIPIDS; STROKE; STENOSIS; LIPOPROTEINS; PREVALENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
J.S. Fineedelstein et al., "PRECURSORS OF EXTRACRANIAL CAROTID ATHEROSCLEROSIS IN THE FRAMINGHAM-STUDY", Neurology, 44(6), 1994, pp. 1046-1050

Abstract

To investigate cardiovascular risk factors and carotid atherosclerosis, we related previously measured risk factors to carotid atherosclerosis as determined by duplex ultrasonography in the Framingham Study cohort. Risk factors measured prospectively on 1,116 cohort members, ages 66 to 93, were related to the severity of carotid atherosclerosis measured by carotid ultrasonography performed during biennial examination no. 20 (1988 to 1990). The degree of carotid atherosclerosis was expressed as a percent carotid stenosis and, for statistical analysis, subjects were divided into four groups according to percent carotid stenosis. The prevalence of significant carotid stenosis in the general population was low-7% in women and 9% in men. A multivariate logistic regression model showed that age, cigarette smoking, systolic blood pressure, and cholesterol were independently related to carotid atherosclerosis. Alcohol consumption was also significant in men, but not in women. In addition, our results indicate that both current and former smoking in both sexes was related to the degree of carotid atherosclerosis.

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Documento generato il 27/11/20 alle ore 02:28:00