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Titolo:
USE OF THE FOURIER-SERIES WINDOW PROTOCOL WITH A ZIGZAG SURFACE COIL IN P-31 NMR HUMAN SKIN SPECTROSCOPY - A THEORETICAL-STUDY
Autore:
BASTIN ME; COWIE AG; MANNERS DN; HANDS LJ; STYLES P;
Indirizzi:
JOHN RADCLIFFE HOSP,MRC,BIOCHEM & CLIN MAGNET RESONANCE SPECT UNIT OXFORD OX3 9DU ENGLAND JOHN RADCLIFFE HOSP,NUFFIELD DEPT SURG OXFORD OX3 9DU ENGLAND
Titolo Testata:
NMR in biomedicine
fascicolo: 5, volume: 9, anno: 1996,
pagine: 201 - 207
SICI:
0952-3480(1996)9:5<201:UOTFWP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CUTANEOUS TISSUE; INVIVO; METABOLISM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
M.E. Bastin et al., "USE OF THE FOURIER-SERIES WINDOW PROTOCOL WITH A ZIGZAG SURFACE COIL IN P-31 NMR HUMAN SKIN SPECTROSCOPY - A THEORETICAL-STUDY", NMR in biomedicine, 9(5), 1996, pp. 201-207

Abstract

The use of a zig-zag surface coil with a three-pulse Fourier Series Window (FSW) has been suggested as a means by which in vivo NMR spectroscopic studies of human skin can be performed. Using direct numerical simulations of the magnetic field profile of a 10 limb zig-zag surfacecoil, the role of the FSW in reducing NMR signals originating from the deeper skeletal muscle layers is examined theoretically, The extent of muscle signal contamination is determined for different coil inter-limb spacings and pulse width settings, The optimum interlimb spacing for studying living human skin, that which minimizes signal contamination and maximizes skin signal collected, is shown to be between 4 and 6 mm, These calculations demonstrate that the FSW and zig-zag surface coil offer a protocol for investigating the metabolism of large areas of surface tissue while keeping signal contamination from the deeper skeletal muscle layers down to an acceptable level.

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Documento generato il 01/10/20 alle ore 04:27:44