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Titolo:
P-31 NMR-STUDIES OF HUMAN SKIN USING A MODIFIED ZIGZAG SURFACE COIL
Autore:
COWIE AG; BASTIN ME; MANNERS DN; HANDS LJ; STYLES P; RADDA GK;
Indirizzi:
JOHN RADCLIFFE HOSP,MRC,BIOCHEM & CLIN MAGNET RESONANCE SPECT UNIT OXFORD OX3 9DU ENGLAND JOHN RADCLIFFE HOSP,MRC,BIOCHEM & CLIN MAGNET RESONANCE SPECT UNIT OXFORD OX3 9DU ENGLAND JOHN RADCLIFFE HOSP,NUFFIELD DEPT SURG OXFORD OX3 9DU ENGLAND
Titolo Testata:
NMR in biomedicine
fascicolo: 5, volume: 9, anno: 1996,
pagine: 195 - 200
SICI:
0952-3480(1996)9:5<195:PNOHSU>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CUTANEOUS TISSUE; HUMAN CALF; INVIVO; SPECTROSCOPY; METABOLISM; MUSCLE; FLAPS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
A.G. Cowie et al., "P-31 NMR-STUDIES OF HUMAN SKIN USING A MODIFIED ZIGZAG SURFACE COIL", NMR in biomedicine, 9(5), 1996, pp. 195-200

Abstract

Results are presented from an in vivo study of human skin in which a zig-zag surface coil together with a three-pulse Fourier Series Window(FSW) protocol have been used to obtain minimally contaminated P-31 skin spectra of the posterior calf, Phantom experiments indicate that while the fall-off in the B-1 field profile of the dg-zag surface coil is superior to conventional surface coil designs, it is still not sufficient on its own to reduce muscle signal contamination to acceptable levels in human studies, The additional spatial localization required is provided by the FSW, which reduces signal contamination to less than 30% of the total signal collected, In a study of 18 normal controls the measured pH was found to be relatively high (7.39 +/- 0.08), whilethe ratios of skin PCr/beta-ATP (1.04 +/- 0.35) and PCr/Pi (1.67 +/- 0.4) were found to be low compared with that of skeletal muscle, In addition, substantial signal from phosphomonoesters and phosphodiesters were also observed.

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Documento generato il 01/10/20 alle ore 04:52:08