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Titolo:
EARLY AND LATE PRESENTATION OF THE OVARIAN HYPERSTIMULATION SYNDROME - 2 DISTINCT ENTITIES WITH DIFFERENT RISK-FACTORS
Autore:
LYONS CAD; WHEELER CA; FRISHMAN GN; HACKETT RJ; SEIFER DB; HANING RV;
Indirizzi:
WOMEN & INFANTS HOSP RHODE ISL,DEPT OBSTET & GYNECOL,101 DUDLEY ST PROVIDENCE RI 02905 WOMEN & INFANTS HOSP RHODE ISL,DEPT OBSTET & GYNECOL PROVIDENCE RI 02905 BROWN UNIV PROVIDENCE RI 02905
Titolo Testata:
Human reproduction
fascicolo: 5, volume: 9, anno: 1994,
pagine: 792 - 799
SICI:
0268-1161(1994)9:5<792:EALPOT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
INVITRO FERTILIZATION; PREVENTION; ESTRADIOL; INDUCTION; OVULATION; WOMEN; IVF;
Keywords:
HCG; IVF; MULTIPLE GESTATION; OHSS; PREDICTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
C.A.D. Lyons et al., "EARLY AND LATE PRESENTATION OF THE OVARIAN HYPERSTIMULATION SYNDROME - 2 DISTINCT ENTITIES WITH DIFFERENT RISK-FACTORS", Human reproduction, 9(5), 1994, pp. 792-799

Abstract

This study was designed to identify clinical predictors for early andlate ovarian hyperstimulation syndrome (OHSS). A retrospective analysis of all 592 in-vitro fertilization (IVF) cycles from the programme'sinception in 1988 up to March 1993 was performed. Six patients (1.0% of cycles) had moderate or severe OHSS presenting 3-7 days post-human chorionic gonadotrophin (HCG), and four patients (0.7% of cycles) had severe OHSS presenting 12-17 days post-HCG. No patient with early OHSSwent on to develop late OHSS, and no patient with late OHSS had demonstrated early OHSS. Stepwise logistic regression showed that early OHSS was predicted by the number of oocytes retrieved (range 18-46) (P = 0.0001) and the oestradiol concentration on the day HCG was given (range 12 122-24 454 pmol/l) (P = 0.0003). Late OHSS was predicted by the number of gestational sacs (range 2-3) on ultrasound 4 weeks after embryo transfer (P = 0.0001) but not by the number of oocytes or oestradiol. Early OHSS was an acute effect of the HCG administered prior to egg retrieval in women with high oestradiol and larger numbers of follicles (range 22-51). Late OHSS was induced by the rising serum concentration of HCG produced by the early pregnancy, and in this series of cases it was associated only with multiple gestation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 08:06:26