Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A NEW EFFICIENT SYNTHESIS OF ETHYL BETA-CARBOLINE-3-CARBOXYLATE (BETA-CCE) AND METHYL 4-METHYL-BETA-CARBOLINE-3-CARBOXYLATE (4-METHYL-BETA-CCM) STARTING FROM INDOLE-2 CARBOXALDEHYDE
Autore:
DEKHANE M; DODD RH;
Indirizzi:
INST CHIM SUBST NAT,CNRS F-91198 GIF SUR YVETTE FRANCE INST CHIM SUBST NAT,CNRS F-91198 GIF SUR YVETTE FRANCE
Titolo Testata:
Tetrahedron
fascicolo: 21, volume: 50, anno: 1994,
pagine: 6299 - 6306
SICI:
0040-4020(1994)50:21<6299:ANESOE>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BENZODIAZEPINE RECEPTOR ANTAGONIST; METHOXY-N-METHYLAMIDES; STREPTOMYCES-LAVENDULAE; AMINO-ACIDS; LAVENDAMYCIN; CARBOLINES; ESTER; DERIVATIVES; OXIDATION; ANALOGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
M. Dekhane e R.H. Dodd, "A NEW EFFICIENT SYNTHESIS OF ETHYL BETA-CARBOLINE-3-CARBOXYLATE (BETA-CCE) AND METHYL 4-METHYL-BETA-CARBOLINE-3-CARBOXYLATE (4-METHYL-BETA-CCM) STARTING FROM INDOLE-2 CARBOXALDEHYDE", Tetrahedron, 50(21), 1994, pp. 6299-6306

Abstract

Ethyl beta-carboline-3-carboxylate (9) and methyl 4-methyl-beta-carboline-3-carboxylate (15) were prepared in high yields hy condensing indole-2-carboxaldehyde (5) (itself prepared by lithium aluminum hydride reduction of the Weinreb amide derived from indole-2-carboxylic acid) with ethyl 2-amino-3,3-diethoxypropionate (6) and methyl 2-amino-3,3-diethoxybutyrate (12), respectively, followed by reduction of the iminebonds formed with sodium cyanoborohydride and cyclization of the resulting amines (8 and 14, respectively) using titanium (IV) chloride.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 21:48:52