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Titolo:
ENTRANCE AND SURVIVAL OF SALMONELLA-TYPHIMURIUM AND YERSINIA-ENTEROCOLITICA WITHIN HUMAN B-CELL AND T-CELL LINES
Autore:
VERJANS GMGM; RINGROSE JH; VANALPHEN L; FELTKAMP TEW; KUSTERS JG;
Indirizzi:
NETHERLANDS OPHTHALM RES INST,DEPT OPHTHALMOIMMUNOL,POB 12141 1100 ACAMSTERDAM NETHERLANDS UNIV AMSTERDAM,DEPT MED MICROBIOL AMSTERDAM NETHERLANDS UNIV UTRECHT,SCH VET MED,INST INFECT DIS & IMMUNOL,DEPT BACTERIOL UTRECHT NETHERLANDS
Titolo Testata:
Infection and immunity
fascicolo: 6, volume: 62, anno: 1994,
pagine: 2229 - 2235
SICI:
0019-9567(1994)62:6<2229:EASOSA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAMMALIAN-CELLS; BACTERIAL ATTACHMENT; ESCHERICHIA-COLI; EPITHELIAL-CELLS; INVASIN PROTEIN; HEP-2 CELLS; ADHESION; PENETRATION; PLASMID; PSEUDOTUBERCULOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
G.M.G.M. Verjans et al., "ENTRANCE AND SURVIVAL OF SALMONELLA-TYPHIMURIUM AND YERSINIA-ENTEROCOLITICA WITHIN HUMAN B-CELL AND T-CELL LINES", Infection and immunity, 62(6), 1994, pp. 2229-2235

Abstract

Lymphocytes, located within the Peyer's patches, might be involved inthe dissemination of enteropathogenic Salmonella typhimurium and Yersinia enterocolitica bacteria. To test this hypothesis, we have investigated the susceptibility of human B- and T-cell lines to bacterial adhesion and invasion. The two S. typhimurium strains analyzed were highly invasive, while the two Y. enterocolitica (0:8) strains adhered to the B- and T-cell lines but did not enter the cell lines in significantamounts. We hypothesize that the incapability of the Y. enterocolitica (0:8) strains to enter the human B- and T-cell lines is most probably due to the bacterial inability to induce the internalization processupon adhesion to both cell lines. Although immortalized B- and T-celllines were used in this study, the results presented suggest the possibility that both cell types could play a role in the dissemination ofintracellularly residing S. typhimurium in vivo.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 15:54:54