Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ALCOHOL, IMMUNOMODULATION, AND DISEASE
Autore:
WATSON RR; BORGS P; WITTE M; MCCUSKEY RS; LANTZ C; JOHNSON MI; MUFTI SI; EARNEST DL;
Indirizzi:
UNIV ARIZONA,SCH MED,DEPT FAMILY & COMMUNITY MED,ALCOHOL RES CTR TUCSON AZ 85724 UNIV ARIZONA,SCH MED,DEPT SURG TUCSON AZ 85724 UNIV ARIZONA,SCH MED,DEPT ANAT TUCSON AZ 85724 UNIV ARIZONA,SCH MED,DEPT PEDIAT TUCSON AZ 85724 UNIV ARIZONA,SCH MED,DEPT PHARMACOL & TOXICOL TUCSON AZ 85724 UNIV ARIZONA,SCH MED,DEPT BUNKYO KU TUCSON AZ 85724
Titolo Testata:
Alcohol and alcoholism
fascicolo: 2, volume: 29, anno: 1994,
pagine: 131 - 139
SICI:
0735-0414(1994)29:2<131:AIAD>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIVER-DISEASE; ETHANOL-CONSUMPTION; KUPFFER; EXPRESSION; MICE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
53
Recensione:
Indirizzi per estratti:
Citazione:
R.R. Watson et al., "ALCOHOL, IMMUNOMODULATION, AND DISEASE", Alcohol and alcoholism, 29(2), 1994, pp. 131-139

Abstract

Recent research findings point to a spectrum of alcohol-induced immune dysfunctions in animal models and humans. Use of alcohol in vivo causes abnormalities in the function and/or structure of a broad array ofcells involved in humoral and cellular immunity, including lymphocytes, Kupffer cells and other macrophages, as well as the endothelium of blood vessels and lymphatics. Regulatory cytokines and neuroendocrine factors can mediate some of these immunomodulatory effects which may be further re-phased, exaggerated or unbalanced by other drugs of misuse. A variety of animal models is available to study acute and chronic alcoholism, non-alcohol drug misuse, AIDS as well as other opportunistic infections, and neoplasias, which hold promise of clarifying the role of alcohol as an immunomodulator.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 19:58:04