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Titolo:
THE RELATIONSHIP BETWEEN AGE AND COGNITIVE IMPAIRMENT IN HIV-1 INFECTION - FINDINGS FROM THE MULTICENTER AIDS COHORT STUDY AND A CLINICAL COHORT
Autore:
VANGORP WG; MILLER EN; MARCOTTE TD; DIXON W; PAZ D; SELNES O; WESCH J; BECKER JT; HINKIN CH; MITRUSHINA M; SATZ P; WEISMAN JD; BUCKINGHAM SL; STENQUIST PK;
Indirizzi:
UNIV CALIF LOS ANGELES,INST NEUROPSYCHIAT,760 WESTWOOD PLAZA LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,SCH MED,DEPT VET AFFAIRS MED CTR LOS ANGELES CA 00000 UNIV CALIF LOS ANGELES,SCH MED,DEPT PSYCHIAT & BEHAV SCI LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,SCH MED,DEPT BIOMATH LOS ANGELES CA 90024 JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH BALTIMORE MD 00000 HOWARD BROWN MEM CLIN CHICAGO IL 00000 UNIV PITTSBURGH,GRAD SCH PUBL HLTH PITTSBURGH PA 00000 UNIV PITTSBURGH,SCH MED PITTSBURGH PA 00000 UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,PACIFIC OAKS MED GRP LOS ANGELES CA 90024 KEITH MED GRP LOS ANGELES CA 00000
Titolo Testata:
Neurology
fascicolo: 5, volume: 44, anno: 1994,
pagine: 929 - 935
SICI:
0028-3878(1994)44:5<929:TRBAAC>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEMENTIA COMPLEX; NEUROPSYCHOLOGICAL PERFORMANCE; ALZHEIMERS-DISEASE; HOMOSEXUAL MEN; UNITED-STATES; PREVALENCE; ABNORMALITIES; DYSFUNCTION; INDIVIDUALS; POPULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
W.G. Vangorp et al., "THE RELATIONSHIP BETWEEN AGE AND COGNITIVE IMPAIRMENT IN HIV-1 INFECTION - FINDINGS FROM THE MULTICENTER AIDS COHORT STUDY AND A CLINICAL COHORT", Neurology, 44(5), 1994, pp. 929-935

Abstract

Previous studies have identified age as a risk factor for many neurologic disorders, and a ''cerebral reserve'' factor has been postulated to explain these findings. This study examined whether age represents a risk factor for HIV-1-related neuropsychological dysfunction. Subjects for study 1 were primarily asymptomatic seropositive (n = 1,066) and seronegative (n = 1,004) nonelderly male community volunteers who completed neuropsychological and reaction time measures. Data analyses revealed a significant effect for age on reaction time and timed neuropsychological measures, but no interaction between age and serostatus. Study 2, employing a similar neuropsychological battery, consisted of 76 seropositive men (29 over age 55) recruited from community outpatient clinics and 47 seronegative controls. We found serostatus and age to have main effects on a number of measures, but a trend for an effectof age-serostatus interaction on only one measure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:50:21