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Titolo:
PSEUDOMONAS SEPSIS DOES NOT CAUSE MORE SEVERE CARDIOVASCULAR DYSFUNCTION IN PATIENTS THAN NON-PSEUDOMONAS SEPSIS
Autore:
PILZ G; MCGINN P; BOEKSTEGERS P; KAAB S; WEIDENHOFER S; WERDAN K;
Indirizzi:
UNIV MUNICH,GROSSHADERN UNIV HOSP,DEPT MED 1,MARCHIONINISTR 15 D-81377 MUNICH GERMANY
Titolo Testata:
Circulatory shock
fascicolo: 4, volume: 42, anno: 1994,
pagine: 174 - 182
SICI:
0092-6213(1994)42:4<174:PSDNCM>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN SEPTIC SHOCK; PULMONARY-CAPILLARY WEDGE; MYOCARDIAL DEPRESSION; MONOCLONAL-ANTIBODY; CARDIOGENIC-SHOCK; ESCHERICHIA-COLI; CANINE MODEL; ILL PATIENTS; APACHE-II; BACTEREMIA;
Keywords:
LEFT VENTRICULAR DYSFUNCTION; LVSWI; MYOCARDIAL DEPRESSION; PSEUDOMONAS AERUGINOSA; SEPTIC SHOCK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
G. Pilz et al., "PSEUDOMONAS SEPSIS DOES NOT CAUSE MORE SEVERE CARDIOVASCULAR DYSFUNCTION IN PATIENTS THAN NON-PSEUDOMONAS SEPSIS", Circulatory shock, 42(4), 1994, pp. 174-182

Abstract

To evaluate the clinical relevance of the experimental findings of a more severe cardiac depression in Pseudomonas (P.) than in non-P. sepsis, we retrospectively compared the hemodynamic data in 26 patients with P. sepsis (20 cases, single pathogen; six cases, more positive cultures with P. than with non-P. species), and 102 with non-P. sepsis. Asin other studies, the left ventricular stroke work index (LVSWI) was used to assess cardiac performance. The two groups (all numbers are means) had a similar disease and sepsis severity profile (P. vs. non-P: septic shock, 81% vs. 87%; APACHE II scores, 29.1 vs. 29.2; Elebute sepsis scores, 18.1 vs. 18.1; mortality, 58% vs. 62%). Preload (pulmonary capillary wedge pressure 15.0 vs. 16.3 mm Hg) and systemic vascular resistance (588 vs 572 dyn . cm(-5) . sec) were comparable. Cardiac performance displayed no significant difference (LVSWI, 42.8 vs. 38.3 g . m/m(2)), a result reproduced in the subgroups with culture-proven bacteremia, with or without preexisting cardiovascular disease or septicshock. Thus, our data suggest that there is no difference in the degree of cardiovascular dysfunction in patients with Pseudomonas comparedto non-Pseudomonas sepsis of otherwise equivalent disease severity. (C) 1994 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 11:48:44