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Titolo:
PULMONARY HEMORRHAGE - A FATAL MANIFESTATION IN IGA NEPHROPATHY
Autore:
LAI FMM; LI EKM; SUEN MWM; LUI SF; LI PKT; LAI KN;
Indirizzi:
CHINESE UNIV HONG KONG SHA TIN HONG KONG CHINESE UNIV HONG KONG,DEPT MED SHA TIN HONG KONG
Titolo Testata:
Archives of pathology and laboratory medicine
fascicolo: 5, volume: 118, anno: 1994,
pagine: 542 - 546
SICI:
0003-9985(1994)118:5<542:PH-AFM>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
HENOCH-SCHONLEIN SYNDROME; SYSTEMIC VASCULITIS; LUNG HEMORRHAGE; GLOMERULONEPHRITIS; CAPILLARITIS; NEPHRITIS; PURPURA; PATIENT; IMMUNE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
F.M.M. Lai et al., "PULMONARY HEMORRHAGE - A FATAL MANIFESTATION IN IGA NEPHROPATHY", Archives of pathology and laboratory medicine, 118(5), 1994, pp. 542-546

Abstract

Two patients with asymptomatic IgA nephropathy (IgAN) and a third patient with chronic renal failure due to IgAN died following a recent onset of dyspnea, hemoptysis, and pulmonary infiltrates. In all cases, the cause of death was respiratory failure attributed to either bronchopneumonia or pulmonary edema, However, no infectious agent was identified. In all three patients, the diagnoses of IgAN and idiopathic pulmonary hemorrhage were established at postmortem examination. Acute alveolar hemorrhage was present in two patients. All three patients had heavy alveolar hemosiderin-laden macrophages, and capillaritis was recognized in two of them. The occurrence of fatal pulmonary hemorrhage in patients with IgAN is rare. Our findings suggested an immune complex-mediated pulmonary injury that was possibly related to the systemic nature of IgAN.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:31:04