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Titolo:
SERUM KERATAN SULFATE LEVELS IN RHEUMATOID-ARTHRITIS - INVERSE CORRELATION WITH RADIOGRAPHIC STAGING
Autore:
HARAOUI B; THONAR EJMA; MARTELPELLETIER J; GOULET JR; RAYNAULD JP; OUELLET M; PELLETIER JP;
Indirizzi:
UNIV MONTREAL,NOTRE DAME HOSP,RES CTR,DEPT MED,DIV RHEUMAT DIS,1560 EST,RUE SHERBROOKE MONTREAL H2L 4M1 PQ CANADA RUSH PRESBYTERIAN ST LUKES MED CTR,DEPT BIOCHEM CHICAGO IL 00000 RUSH PRESBYTERIAN ST LUKES MED CTR,DEPT INTERNAL MED CHICAGO IL 00000 STANFORD UNIV,SCH MED,DIV RHEUMATOL & IMMUNOL STANFORD CA 00000
Titolo Testata:
Journal of rheumatology
fascicolo: 5, volume: 21, anno: 1994,
pagine: 813 - 817
SICI:
0315-162X(1994)21:5<813:SKSLIR>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
OSTEO-ARTHRITIS; ANTIRHEUMATIC DRUGS; SYNOVIAL-FLUID; CARTILAGE; PROTEOGLYCAN; BLOOD; OSTEOARTHRITIS; ASSOCIATION;
Keywords:
KERATAN SULFATE; RADIOGRAPHIC STAGING; RHEUMATOID ARTHRITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
B. Haraoui et al., "SERUM KERATAN SULFATE LEVELS IN RHEUMATOID-ARTHRITIS - INVERSE CORRELATION WITH RADIOGRAPHIC STAGING", Journal of rheumatology, 21(5), 1994, pp. 813-817

Abstract

Objective. To correlate the serum levels of keratan sulfate (KS) in patients with rheumatoid arthritis (RA) with different clinical and radiographic variables. Methods. Serum KS levels were measured in 85 patients with RA and 41 age matched controls. Patients with RA were classified according to their disease activity, the presence of rheumatoid factor, the medication prescribed, and to the severity of the joint radiographic changes: Results. Patients with RA had significantly (p < 0.02) higher levels of serum KS compared to the healthy controls. More significantly, there was an inverse correlation of the serum KS levels with the disease activity (p = 0.02) and the severity of the radiographic changes (p = 0.012). Conclusions. Serum KS levels appear to correlate with the severity of articular cartilage damage in RA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 04:32:42