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Titolo:
UV-B RADIATION-INDUCED CATARACT IN THE ROYAL-COLLEGE OF SURGEONS RAT
Autore:
BREADSELL RO; WEGENER A; BREIPOHL W; HIRST LW;
Indirizzi:
UNIV QUEENSLAND,PRINCESS ALEXANDRA HOSP,DEPT SURG,DIV OPHTHALMOL,IPSWICH RD BRISBANE QLD 4072 AUSTRALIA UNIV BONN,INST EXPTL OPHTHALMOL W-5300 BONN GERMANY
Titolo Testata:
Ophthalmic research
, volume: 26, anno: 1994, supplemento:, 1
pagine: 84 - 89
SICI:
0030-3747(1994)26:<84:URCITR>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTERIOR SUBCAPSULAR CATARACTS; LIPID-PEROXIDATION PRODUCTS; ULTRAVIOLET-RADIATION; SQUIRREL LENS; EXPOSURE; LIGHT; INITIATION; INVIVO;
Keywords:
CATARACT; UV-B RADIATION; RSC RAT; LENS FIBER CELL; RAT LENS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
R.O. Breadsell et al., "UV-B RADIATION-INDUCED CATARACT IN THE ROYAL-COLLEGE OF SURGEONS RAT", Ophthalmic research, 26, 1994, pp. 84-89

Abstract

Cataractogenesis was studied in Royal College of Surgeon (RCS) rats which carry a recessive gene for retinal dystrophy. To examine the impact of this syndrome on cataractogenesis, the cortical lens damage in the UV-B radiation-induced cataract and in the hereditary cataract werecompared in homozygous (affected) and heterozygous (unaffected) pink-eyed, tan-hooded RCS rats. The findings from this investigation suggest that the early changes in both the radiation-induced anterior subcapsular cataract and the hereditary posterior subcapsular cataract are at the level of the fibre cell membrane.

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Documento generato il 22/09/20 alle ore 12:53:51