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Titolo:
GENERAL VERSUS REGIONAL ANESTHESIA AND PLATELET-AGGREGATION IN MINOR SURGERY
Autore:
NAESH O; HINDBERG I; FRIIS J; CHRISTIANSEN C;
Indirizzi:
GOTHENBURG UNIV,SAHLGRENS HOSP,DEPT ANAESTHESIA & INTENS CARE S-41345GOTHENBURG SWEDEN
Titolo Testata:
European journal of anaesthesiology
fascicolo: 3, volume: 11, anno: 1994,
pagine: 169 - 173
SICI:
0265-0215(1994)11:3<169:GVRAAP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Keywords:
BLOOD, PLATELET AGGREGATION; ANESTHESIA; ANESTHETIC TECHNIQUE, EPIDURAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
O. Naesh et al., "GENERAL VERSUS REGIONAL ANESTHESIA AND PLATELET-AGGREGATION IN MINOR SURGERY", European journal of anaesthesiology, 11(3), 1994, pp. 169-173

Abstract

In order to evaluate the impact of minor surgery on platelet aggregability and the effect of anaesthesia on this parameter, we allocated 14otherwise healthy men for inguinal herniotomy to either general anaesthesia (n=7) or lumbar epidural anaesthesia (n=7). Platelet aggregation threshold to adenosine diphosphate (ADP-threshold) was measured before and after anaesthesia, prior to surgery, at the end of surgery and during the following hours as well as on the first post-operative morning. General anaesthesia did not affect ADP-threshold while epidural analgesia itself induced a significant increase. During and soon after surgery the ADP-threshold increased in those receiving general anaesthesia while in those receiving epidural analgesia the ADP-threshold returned to pre-operative levels. On the first post-operative morning both groups showed a significantly lower ADP-threshold as compared to thepre-operative level. Surgery induced an increase in 3'5' cyclic-adenosine monophosphate (cAMP). This adrenergic response was attenuated by epidural analgesia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 07:49:00