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Titolo:
2 MOLECULAR-FORMS OF PEPTIDE YY (PYY) ARE ABUNDANT IN HUMAN BLOOD - CHARACTERIZATION OF A RADIOIMMUNOASSAY RECOGNIZING PYY-1-36 AND PYY-3-36
Autore:
GRANDT D; SCHIMICZEK M; BEGLINGER C; LAYER P; GOEBELL H; EYSSELEIN VE; REEVE JR;
Indirizzi:
UNIV ESSEN GESAMTHSCH,DEPT GASTROENTEROL,HUFELANDSTR 55 D-45147 ESSENGERMANY KANTONSSPITAL BASEL,DEPT GASTROENTEROL BASEL SWITZERLAND UNIV CALIF LOS ANGELES,HARBOR MED CTR,DEPT GASTROENTEROL TORRANCE CA 90509 UNIV CALIF LOS ANGELES,VA,CURE,CTR GASTROENTER BIOL LOS ANGELES CA 90073
Titolo Testata:
Regulatory peptides
fascicolo: 2, volume: 51, anno: 1994,
pagine: 151 - 159
SICI:
0167-0115(1994)51:2<151:2MOPY(>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
GASTRIC-ACID SECRETION; NEUROPEPTIDE-Y; STRUCTURAL CHARACTERIZATION; EXOCRINE PANCREAS; RAT; RELEASE; GUT; DOG; POLYPEPTIDE; INHIBITION;
Keywords:
PYY; RADIOIMMUNOASSAY; MOLECULAR HETEROGENEITY; HUMAN PLASMA; GASTROINTESTINAL HORMONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
D. Grandt et al., "2 MOLECULAR-FORMS OF PEPTIDE YY (PYY) ARE ABUNDANT IN HUMAN BLOOD - CHARACTERIZATION OF A RADIOIMMUNOASSAY RECOGNIZING PYY-1-36 AND PYY-3-36", Regulatory peptides, 51(2), 1994, pp. 151-159

Abstract

Two endogenous forms of PW are abundant in man and dog, PW 1-36 (PYY-I) and PYY 3-36 (PYY-II). PW-II is a major molecular form of PW in human colon, but it is not known, whether PYY-II is also released into the circulating blood. Several radioimmunoassays for measuring PYY-I in plasma have been developed, but it has not been reported, whether theyequally detect PYY-II, We characterize a radioimmunoassay for measuring PYY in human plasma which equally recognizes PW-I and PYY-II. Usingthis radioimmunoassay and reversed phase HPLC we demonstrate the existence of two forms of PYY in human blood, coeluting with synthetic PW-I and PW-II.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 02:06:49