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Titolo:
AGE AFFECTS BRAIN PROTEIN-SYNTHESIS IN RATS
Autore:
HAYASE K; YOKOGOSHI H;
Indirizzi:
AICHI UNIV EDUC,DEPT HOME ECON KARIYA AICHI 448 JAPAN UNIV SHIZUOKA,SCH FOOD & NUTR SCI,NUTR BIOCHEM LAB YADA SHIZUOKA 422 JAPAN
Titolo Testata:
The Journal of nutrition
fascicolo: 5, volume: 124, anno: 1994,
pagine: 683 - 688
SICI:
0022-3166(1994)124:5<683:AABPIR>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATIC POLYRIBOSOME PROFILES; WHOLE-BODY; GROWTH; SKELETAL; TURNOVER; QUALITY; MUSCLE; DISAGGREGATION; INTESTINE; QUANTITY;
Keywords:
AGE; RNA; BRAIN; PROTEIN SYNTHESIS; RATS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
K. Hayase e H. Yokogoshi, "AGE AFFECTS BRAIN PROTEIN-SYNTHESIS IN RATS", The Journal of nutrition, 124(5), 1994, pp. 683-688

Abstract

The purpose of the present study was to determine whether age affected the rate of brain protein synthesis in rats. Experiments were conducted on three groups of rats, ages 4, 7 or 24 wk. The fractional rates of protein synthesis in brain, liver and kidney decreased and the RNA concentration (mg RNA/g protein) declined with age. In brain, liver and kidney, the RNA concentrations were significantly correlated with the fractional rates of protein synthesis. The RNA activity [g protein synthesized/(g RNA.d)] was not related to the fractional rate of protein synthesis in any organs except cerebral cortex. The results suggest that the rate of protein synthesis in brain declines with age after weaning, and that RNA concentration is at least partly related to the fractional rate of brain protein synthesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:25:13