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Titolo:
BIRTH-DEFECTS AND PARENTAL CONSANGUINITY IN NORWAY
Autore:
STOLTENBERG C; MAGNUS P; LIE RT; DALTVEIT AK; IRGENS LM;
Indirizzi:
NATL PUBL HLTH INST,POB 4404 N-0403 OSLO NORWAY UNIV BERGEN,MED BIRTH REGISTRY NORWAY BERGEN NORWAY
Titolo Testata:
American journal of epidemiology
fascicolo: 5, volume: 145, anno: 1997,
pagine: 439 - 448
SICI:
0002-9262(1997)145:5<439:BAPCIN>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONGENITAL-MALFORMATIONS; REPRODUCTIVE-BEHAVIOR; HEALTH; POPULATION; MARRIAGES; FREQUENCY; MORTALITY; INEQUALITIES; PAKISTAN; MATINGS;
Keywords:
ABNORMALITIES; CONSANGUINITY; EDUCATION; ETHNIC GROUPS; GENETICS; SOCIAL CLASS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
C. Stoltenberg et al., "BIRTH-DEFECTS AND PARENTAL CONSANGUINITY IN NORWAY", American journal of epidemiology, 145(5), 1997, pp. 439-448

Abstract

The study compares frequencies of birth defects between immigrant groups and the rest of the Norwegian population in Norway and estimates the influence of consanguinity and socioeconomic factors on these frequencies. The authors studied all 1.56 million births in Norway from 1967 to 1993, Of these, 7,494 children had two Pakistani parents, 84,688 had one Norwegian and one immigrant parent, and 25,891 had two immigrant parents from countries other than Pakistan, The risk of birth defects relative to the Norwegian group was 0.98 (95% confidence interval 0.92-1.03) in the group with one foreign and one Norwegian parent, 1.39(95% confidence interval 1.22-1.60) in the group with two Pakistani parents, and 1.04 (95% confidence interval 0.95-1.14) in the group withtwo parents from other foreign countries; 0.1% of the Norwegian and 30.1% of the Pakistani children had parents who were first cousins. There was no difference in risk between children of nonconsanguineous Pakistani parents and the other groups, The relative risk of birth defects among children whose parents were first cousins was about 2 in all groups. Among the Pakistani, 28% of all birth defects could be attributed to consanguinity. Low paternal educational level was associated with a slightly increased risk in the Norwegian group, while independent effects of parental educational levels were not found in any other groups.

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Documento generato il 02/12/20 alle ore 06:49:05