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Titolo:
BRONCHOMOTOR AGENTS AND HYSTERESIS OF COLLATERAL RESISTANCE IN DOG LOBE
Autore:
KIKUCHI R; KIKUCHI K; HILDEBRANDT J; SEKIZAWA K; YAMAYA M; SASAKI H;
Indirizzi:
TOHOKU UNIV,SCH MED,DEPT GERIATR MED SENDAI 980 JAPAN TOHOKU UNIV,SCH MED,DEPT GERIATR MED SENDAI 980 JAPAN
Titolo Testata:
Respiration physiology
fascicolo: 2-3, volume: 96, anno: 1994,
pagine: 127 - 137
SICI:
0034-5687(1994)96:2-3<127:BAAHOC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIFFERENTIAL RESPONSES; LUNG-VOLUME; PIG LUNGS; HISTAMINE; VENTILATION; AIRWAYS;
Keywords:
COLLATERAL VENTILATION, SMOOTH MUSCLE TONE; MAMMALS, DOG; SMOOTH MUSCLE, TONE, BRONCHIAL, COLLATERAL CHANNELS; VENTILATION, COLLATERAL, SMOOTH MUSCLE TONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
R. Kikuchi et al., "BRONCHOMOTOR AGENTS AND HYSTERESIS OF COLLATERAL RESISTANCE IN DOG LOBE", Respiration physiology, 96(2-3), 1994, pp. 127-137

Abstract

The effect of smooth muscle tone on hysteresis of collateral channelswas examined and compared with that of airways, in freshly excised dog lobes. A double lumen catheter was sealed into a branch off the mainbronchus, and air (Vs) flowed through the outer lumen while the pressure in the segment (Ps) was measured by the inner lumen. Collateral conductance (Gcoll) was calculated as Gcoll = Vs/Ps. In another series of experiments a pleural capsule was used to measure either segmental airway flow (Vsaw) or capsule pressure (Pcap). Segmental airway conductance (Gsaw) was calculated as Gsaw = Vsaw/(Ps-Pcap). Hysteresis for Gcoll vs lung volume (VL) curves were almost absent in control and afterisoproterenol inflation Gcoll was greater than deflation Gcoll at a given VL (clockwise history). Conversely, after histamine Gcoll vs VL curves showed a counterclockwise history. The behaviors of Gcoll and Gsaw against a bronchomotor agent were similar. We conclude that major collateral channels have muscular walls, and being that of an airway type.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/08/20 alle ore 15:20:27