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Titolo:
PLEOMORPHIC XANTHOASTROCYTOMA - REPORT OF 6 CASES WITH SPECIAL CONSIDERATION OF DIAGNOSTIC AND THERAPEUTIC PITFALLS
Autore:
TONN JC; PAULUS W; WARMUTHMETZ M; SCHACHENMAYR W; SORENSEN N; ROOSEN K;
Indirizzi:
UNIV WURZBURG,DEPT NEUROSURG,JOSEF SCHNEIDER STR 11 D-97080 WURZBURG GERMANY UNIV WURZBURG,INST PATHOL D-97080 WURZBURG GERMANY UNIV WURZBURG,INST NEURORADIOL D-97080 WURZBURG GERMANY UNIV WURZBURG,INST PEDIAT NEUROSURG D-97080 WURZBURG GERMANY UNIV GIESSEN,INST NEUROPATHOL GIESSEN GERMANY
Titolo Testata:
Surgical neurology
fascicolo: 2, volume: 47, anno: 1997,
pagine: 162 - 169
SICI:
0090-3019(1997)47:2<162:PX-RO6>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN-TUMORS; CLASSIFICATION; FEATURES;
Keywords:
GLIOMA; PLEOMORPHIC XANTHOASTROCYTOMA; MAGNETIC RESONANCE IMAGING (MRI);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
J.C. Tonn et al., "PLEOMORPHIC XANTHOASTROCYTOMA - REPORT OF 6 CASES WITH SPECIAL CONSIDERATION OF DIAGNOSTIC AND THERAPEUTIC PITFALLS", Surgical neurology, 47(2), 1997, pp. 162-169

Abstract

BACKGROUND Pleomorphic xanthoastrocytoma (PXA) is a rare clinicopathologic entity that occurs typically in young patients. improved neuroradiologic techniques, especially gadolinium-enhanced magnetic resonanceimaging (MRI), reveal a characteristic tumor appearance. METHODS We present six cases of PXA operated on with unusual clinical course, elucidating different clinical implications. RESULTS Two patients showed subsequent progression into a malignant glioma, one case was a primary anaplastic PXA. The latter case had not previously been reported in the literature, Increased mitotic activity seems to indicate a worse clinical course; whereas focal infiltration of the brain does not necessarily lead to malignant transformation. CONCLUSIONS Surgical removal isthe treatment of choice. A consequent follow-up is mandatory in orderto detect a potentially malignant recurrence as early as possible andto select patients who need additional therapy. (C) 1997 by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/08/20 alle ore 13:17:31