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Titolo:
AGGREGATION EFFECTS IN WHOLE-BLOOD - INFLUENCE OF TIME AND SHEAR RATEMEASURED USING ULTRASOUND
Autore:
SHEHADA REN; COBBOLD RSC; MO LYL;
Indirizzi:
UNIV TORONTO,INST BIOMED ENGN TORONTO M5S 1A4 ON CANADA GE CO,MED SYST MILWAUKEE WI 53201
Titolo Testata:
Biorheology
fascicolo: 1, volume: 31, anno: 1994,
pagine: 115 - 135
SICI:
0006-355X(1994)31:1<115:AEIW-I>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONSTITUTIVE EQUATION; ECHOGENICITY; FLOW; ERYTHROCYTES; FREQUENCY;
Keywords:
ULTRASOUND; BLOOD ECHOGENICITY; ERYTHROCYTE AGGREGATION; SHEAR RATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
R.E.N. Shehada et al., "AGGREGATION EFFECTS IN WHOLE-BLOOD - INFLUENCE OF TIME AND SHEAR RATEMEASURED USING ULTRASOUND", Biorheology, 31(1), 1994, pp. 115-135

Abstract

Ultrasound B-mode imaging (7 MHz) was used to measure blood echogenicity and velocity profiles simultaneously as they developed with axial distance for a steady flow of 28% hematocrit whole blood flowing in a long (> 60 D) large diameter (D = 2.54 cm) tube. At selected sites along the flow axis, velocity profiles were measured using block matching(cross correlation) between successive digitized images with a known time separation; from these shear rate profiles were calculated. The corresponding echogenicity profiles were also determined by averaging the digitized images. It was found that over a range of low shear rates, the echogenicity is enhanced in a manner similar to the previously reported influence on aggregation. Evidence is presented confirming theimportant role of aggregation in controlling the echogenicity. The transient effects of abrupt flow stoppage were studied and shown to provide useful insights into aggregation kinetics. Based on the above results, a detailed explanation is provided of the echogenicity variationsseen in B-mode ultrasound images of slow-moving blood.

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Documento generato il 05/12/20 alle ore 23:55:55