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Titolo:
STRUCTURE OF FUCOSE BRANCHES IN THE GLYCOSAMINOGLYCAN FROM THE BODY-WALL OF THE SEA-CUCUMBER STICHOPUS-JAPONICUS
Autore:
KARIYA Y; WATABE S; KYOGASHIMA M; ISHIHARA M; ISHII T;
Indirizzi:
SEIKAGAKU CORP,TOKYO RES INST,3-1253 TATENO TOKYO 207 JAPAN UNIV TOKYO,GRAD SCH AGR & LIFE SCI,LAB AQUAT MOL BIOL & BIOTECHNOL TOKYO 113 JAPAN FORESTRY & FOREST PROD RES INST IBARAKI OSAKA 305 JAPAN
Titolo Testata:
Carbohydrate research
fascicolo: 3, volume: 297, anno: 1997,
pagine: 273 - 279
SICI:
0008-6215(1997)297:3<273:SOFBIT>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHONDROITIN SULFATE-E; DEPOLYMERIZATION; REDUCTION;
Keywords:
FUCOSE BRANCH; GLYCOSAMINOGLYCAN; METHYLATION ANALYSIS; SEA CUCUMBER; SULFATE SUBSTITUTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
Y. Kariya et al., "STRUCTURE OF FUCOSE BRANCHES IN THE GLYCOSAMINOGLYCAN FROM THE BODY-WALL OF THE SEA-CUCUMBER STICHOPUS-JAPONICUS", Carbohydrate research, 297(3), 1997, pp. 273-279

Abstract

Fucose-branched chondroitin sulfate E was prepared from the body wallof sea cucumber Stichopus japonicus. The purified glycosaminoglycan (GAG) was chemically desulfated, followed by carboxyl reduction. Intact, desulfated, and desulfated/carboxyl-reduced GAG fractions were subjected to per-O-methylation. GC-MS analyses of the resultant partially methylated alditol acetates demonstrated that the fucose branch is formed by two fucopyranosyl residues linked glycosidically through position (1 --> 3), and that the fucose branch and glucuronic acid are almostequimolar. In addition, it was elucidated that about 20% of the branches stretch from O-3 position of a glucuronic acid moiety of the core chondroitin sulfate polymer, while remaining fucose branches are postulated to protrude from O-4 and/or O-6 position(s) of a N-acetylgalactosamine moiety. This fucose branch was also confirmed to be highly sulfated according to six kinds of substitution pattern in methylation analysis. [GRAPHICS] (C) 1997 Elsevier Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 16:06:48