Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ACUTE AND CHRONIC NICOTINE EFFECTS ON MULTIPLE-SCHEDULE BEHAVIOR - ORAL AND SE ROUTES
Autore:
LAU CE; SPEAR DJ; FALK JL;
Indirizzi:
RUTGERS STATE UNIV,DEPT PSYCHOL,BUSCH CAMPUS NEW BRUNSWICK NJ 08903 RUTGERS STATE UNIV,DEPT PSYCHOL NEW BRUNSWICK NJ 08903
Titolo Testata:
Pharmacology, biochemistry and behavior
fascicolo: 1, volume: 48, anno: 1994,
pagine: 209 - 215
SICI:
0091-3057(1994)48:1<209:AACNEO>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
TOLERANCE; RATS; PERFORMANCE;
Keywords:
NICOTINE; MULTIPLE SCHEDULE; SCHEDULE-INDUCED POLYDIPSIA; FIXED-INTERVAL SCHEDULE; FIXED-RATIO SCHEDULE; NICOTINE TOLERANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
C.E. Lau et al., "ACUTE AND CHRONIC NICOTINE EFFECTS ON MULTIPLE-SCHEDULE BEHAVIOR - ORAL AND SE ROUTES", Pharmacology, biochemistry and behavior, 48(1), 1994, pp. 209-215

Abstract

For rats responding on a 3 h FI 4 min FR 20 schedule of food reinforcement, presession SC nicotine doses (0.1-0.8 mg/kg) produced depression in all responding followed by stimulation of FI responding that was dependent upon both time and dose. With daily presession 0.8 mg/kg SC nicotine injections for 9 days, no tolerance to the depressive or stimulatory effects of nicotine occurred. When nicotine solutions were orally self-administered by presession exposure to 3 h of schedule-induced polydipsia, the subsequent FR responding was unaffected, but the degree of FI response stimulation and its duration occurred in a dose-related fashion (1.18-4.10 mg/kg). Prolonged daily sessions of oral nicotine self-administration provide a technique for investigating the effects of chronic exposure to nicotine. The postingestive effects of nicotine reveal stimulatory effects that last for at least 3 h.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 02:50:06