Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
MAGNETIZATION-TRANSFER - THEORY AND CLINICAL-APPLICATIONS IN NEURORADIOLOGY
Autore:
GROSSMAN RI; GOMORI JM; RAMER KN; LEXA FJ; SCHNALL MD;
Indirizzi:
HOSP UNIV PENN,DEPT RADIOL,3400 SPRUCE ST PHILADELPHIA PA 19104
Titolo Testata:
Radiographics
fascicolo: 2, volume: 14, anno: 1994,
pagine: 279 - 290
SICI:
0271-5333(1994)14:2<279:M-TACI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSFER CONTRAST; PROTEIN SOLUTIONS; CROSS-RELAXATION; ANGIOGRAPHY; MECHANISMS; BRAIN; NMR;
Keywords:
BRAIN, DISEASES, 10.871; BRAIN, HEMORRHAGE; BRAIN, INFECTION, 10.2068, 144.25; BRAIN, MR, 10.121417; BRAIN NEOPLASMS, 10.38; BRAIN NEOPLASMS, MR, 10.121417; MAGNETIC RESONANCE (MR), MAGNETIZATION TRANSFER CONTRAST, 10.121417;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
R.I. Grossman et al., "MAGNETIZATION-TRANSFER - THEORY AND CLINICAL-APPLICATIONS IN NEURORADIOLOGY", Radiographics, 14(2), 1994, pp. 279-290

Abstract

Magnetization transfer, a new technique for improving image contrast in magnetic resonance (MR) imaging, is based on application of off-resonance radio-frequency pulses and observing their effects on MR images, as well as measuring the signal intensity with and without application of the pulses (ie, magnetization transfer ratio [MTR]). MTRs can beused to detect changes in the structural status of brain parenchyma that may or may not be visible with standard MR techniques. Use of MTRsmay allow subcategorization of multiple sclerosis lesions into those with very low MTR (demyelinated lesions) and slightly decreased MTR (edematous lesions). In cases of wallerian degeneration, use of MTRs appears to allow reliable detection of changes undetectable with MR imaging or even light microscopy. In cases of infection with human immunodeficiency virus, MTRs seem to indicate that the macromolecular structure of white matter remains intact until relatively late in the course of disease. In cases of metastatic disease, MTRs of brain lesions indicate structural changes beyond the extent of the lesions seen on standard MR images. These findings may be due to chronic edema, myelin loss,and perhaps previous undetected tumor. In addition to being a new method of providing contrast, the magnetization transfer technique enables semiquantitative, reproducible characterization of tissue and pathologic entities, which could substantially improve the specificity of MRimaging.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 16:05:58