Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
MULTICENTER TRIAL VALIDATION FOR QUANTITATIVE-ANALYSIS OF SAME-DAY REST-STRESS TECHNETIUM-99M-SESTAMIBI MYOCARDIAL TOMOGRAMS
Autore:
VANTRAIN KF; GARCIA EV; MADDAHI J; AREEDA J; COOKE CD; KIAT H; SILAGAN G; FOLKS R; FRIEDMAN J; MATZER L; GERMANO G; BATEMAN T; ZIFFER J; DEPUEY EG; FINKBENNETT D; CLONINGER K; BERMAN DS;
Indirizzi:
CEDARS SINAI MED CTR,DEPT NUCL MED,8700 BEVERLY BLVD LOS ANGELES CA 90048 UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT IMAGING NUCLMED LOS ANGELES CA 90048 UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,DIV CARDIOL LOS ANGELES CA 90048 EMORY UNIV,SCH MED ATLANTA GA 30322
Titolo Testata:
The Journal of nuclear medicine
fascicolo: 4, volume: 35, anno: 1994,
pagine: 609 - 618
SICI:
0161-5505(1994)35:4<609:MTVFQO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; EMISSION COMPUTED-TOMOGRAPHY; TC-99M 2-METHOXY-ISOBUTYL-ISONITRILE; CLINICAL-DIAGNOSIS; TL-201 TOMOGRAPHY; HEART-DISEASE; EXERCISE; PERFUSION; SPECT; QUANTIFICATION;
Keywords:
MULTICENTER TRIAL; CORONARY ARTERY DISEASE; TECHNETIUM-99M-SESTAMIBI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
K.F. Vantrain et al., "MULTICENTER TRIAL VALIDATION FOR QUANTITATIVE-ANALYSIS OF SAME-DAY REST-STRESS TECHNETIUM-99M-SESTAMIBI MYOCARDIAL TOMOGRAMS", The Journal of nuclear medicine, 35(4), 1994, pp. 609-618

Abstract

The accuracy of an automated quantitative analysis of same-day rest/stress Tc-99m sestamibi SPECT images for detection and localization of coronary artery disease (CAD) was assessed in a multicenter trial consisting of 161 patients from 7 different clinical sites utilizing various camera computer systems. Methods: Of the 161 patients, 102 had angiographically documented coronary artery disease, 22 had normal coronary arteriograms, and 37 had a low (< 5% likelihood of coronary artery disease based on their age, sex, symptoms and the results of their exercise electrocardiograms. The patients were studied using previously optimized image acquisition and processing protocols. An additional population consisting of 45 patients with single-vessel disease were evaluated to determine the optimal criteria for detection of CAD, Results: The quantitative analysis method was associated with an overall sensitivity of 87%, specificity of 36%, and normalcy rate (true negative rate in the tow likelihood patients) of 81%. Sensitivity for overall detection of disease was similar (90%) in patients with and without myocardial infarction (90% versus 89%). The sensitivities and specificities for identification of disease in individual coronary arteries were, respectively, 69% and 76% for LAD, 70% and 80% for LCX, and 77% and 85% for RCA. Conclusion: The results of this study demonstrate that the new objective quantitative method for analysis of same-day rest/stress Te-99m sestamibi SPECT images is accurate for detection and localization of CAD and correlates highly with expert visual interpretation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 22:12:14