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Titolo:
IN-VIVO MORPHOMETRY OF PLANUM TEMPORALE ASYMMETRY IN FIRST-EPISODE SCHIZOPHRENIA
Autore:
KLEINSCHMIDT A; FALKAI P; HUANG Y; SCHNEIDER T; FURST G; STEINMETZ H;
Indirizzi:
MAX PLANCK INST BIOPHYS CHEM,POSTFACH 2841 W-3400 GOTTINGEN GERMANY UNIV DUSSELDORF,DEPT NEUROL W-4000 DUSSELDORF GERMANY UNIV DUSSELDORF,DEPT PSYCHIAT W-4000 DUSSELDORF GERMANY UNIV DUSSELDORF,DEPT RADIOL W-4000 DUSSELDORF GERMANY
Titolo Testata:
Schizophrenia research
fascicolo: 1, volume: 12, anno: 1994,
pagine: 9 - 18
SICI:
0920-9964(1994)12:1<9:IMOPTA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; MAGNETIC-RESONANCE; STRUCTURAL ABNORMALITIES; AUDITORY HALLUCINATIONS; CEREBRAL ASYMMETRY; LIMBIC SYSTEM; BRAIN; LOBE; POSTMORTEM; VOLUME;
Keywords:
MAGNETIC RESONANCE IMAGING; BRAIN ANATOMY; TEMPORAL LOBE; LATERALITY; AUDITORY HALLUCINATION; (SCHIZOPHRENIA);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
51
Recensione:
Indirizzi per estratti:
Citazione:
A. Kleinschmidt et al., "IN-VIVO MORPHOMETRY OF PLANUM TEMPORALE ASYMMETRY IN FIRST-EPISODE SCHIZOPHRENIA", Schizophrenia research, 12(1), 1994, pp. 9-18

Abstract

Magnetic resonance imaging is a promising tool for in vivo analysis of the neuropathology underlying schizophrenia. One of the most consistent features emerging from the majority of published studies is the lateralization of pathological findings, and this has led to hypotheses of impaired hemispheric specialization in schizophrenia. In previous work, we have validated morphometry of supratemporal language-related cortex using high-resolution magnetic resonance imaging and analyzed the relation of the so defined planum temporale to functional parametersof hemispheric specialization. In the present study, we examined planum temporale structural asymmetry in first-episode schizophrenics. Asymmetry coefficients obtained in these patients did not differ significantly from those in equally right-handed controls and were not correlated to standard psychopathological measures. These data are contrastedwith other studies reporting lateralized brain pathology in schizophrenia with special emphasis on methodological considerations in neuroimaging procedures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 00:31:19