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Titolo:
LESIONS OF THE PEDUNCULOPONTINE TEGMENTAL NUCLEUS DO NOT ALTER DELAYED NONMATCHING TO POSITION ACCURACY
Autore:
STECKLER T; KEITH AB; SAHGAL A;
Indirizzi:
NEWCASTLE GEN HOSP,MRC,NEUROCHEM PATHOL UNIT,WESTGATE RD NEWCASTLE TYNE NE4 6BE TYNE & WEAR ENGLAND
Titolo Testata:
Behavioural brain research
fascicolo: 1, volume: 61, anno: 1994,
pagine: 107 - 112
SICI:
0166-4328(1994)61:1<107:LOTPTN>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; CONDITIONAL DISCRIMINATION; CHOLINERGIC SYSTEM; BASAL FOREBRAIN; MEMORY; RATS; FORNIX; ANTINOCICEPTION; MECHANISMS; DISRUPTION;
Keywords:
ACETYLCHOLINE; DELAYED-NON-MATCHING TO POSITION; PEDUNCULOPONTINE NUCLEUS; RECOGNITION MEMORY; SIGNAL DETECTION THEORY; RAT;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
T. Steckler et al., "LESIONS OF THE PEDUNCULOPONTINE TEGMENTAL NUCLEUS DO NOT ALTER DELAYED NONMATCHING TO POSITION ACCURACY", Behavioural brain research, 61(1), 1994, pp. 107-112

Abstract

The cholinergic pedunculopontine tegmental nucleus, located in the brainstem, and part of the reticular formation, has traditionally been linked to motor function, sleep and arousal, but has recently been implicated in cognition. To investigate this possibility, rats with radiofrequency lesions were tested on a delayed non-matching to position task, a test for spatial recognition memory abilities. Data were analysedaccording to the methods of signal detection theory. Lesions of the pedunculopontine nucleus did not produce marked deficits in accuracy, although there was some evidence to suggest that motivational processescould have been affected.

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Documento generato il 28/03/20 alle ore 13:52:07