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Titolo:
THE EFFECT OF SUSTAINED POSITIVE AIRWAY PRESSURE ON DERIVED CARDIAC-OUTPUT IN CHILDREN
Autore:
CLOUGH JB; DUNCAN AW; SLY PD;
Indirizzi:
SOUTHAMPTON GEN HOSP SOUTHAMPTON SO9 4XY HANTS ENGLAND WESTERN AUSTRALIAN RES INST CHILD HLTH,DIV CLIN SCI SUBIACO WA AUSTRALIA PRINCESS MARGARET HOSP CHILDREN SUBIACO WA AUSTRALIA
Titolo Testata:
Anaesthesia and intensive care
fascicolo: 1, volume: 22, anno: 1994,
pagine: 30 - 34
SICI:
0310-057X(1994)22:1<30:TEOSPA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
END-EXPIRATORY PRESSURE; LEFT-VENTRICULAR PERFORMANCE;
Keywords:
HEART, CARDIAC OUTPUT; CHILDREN; POSITIVE AIRWAY PRESSURE; VENTILATION, POSITIVE AIRWAY PRESSURE; CARDIAC OUTPUT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
J.B. Clough et al., "THE EFFECT OF SUSTAINED POSITIVE AIRWAY PRESSURE ON DERIVED CARDIAC-OUTPUT IN CHILDREN", Anaesthesia and intensive care, 22(1), 1994, pp. 30-34

Abstract

It is well established that the improvement in gas exchange that occurs with positive pressure ventilation may come at the expense of a decrease in cardiac output and oxygen delivery. Clinical observation suggests that children and infants may be more resistant than adults to the falls in cardiac output induced by positive airway pressure. The aims of this study were to quantify the effect of a sustained increase inintrathoracic pressure on cardiac output and stroke volume, and to determine whether this change is age-related. Twenty-eight children undergoing general anaesthesia were studied. Cardiac output was derived using pulsed wave Doppler techniques at four different levels of sustained positive airway pressure, and stroke volume was calculated. The relationship between airway pressure and both cardiac output and stroke volume was examined using a general linear model which included age as a continuous variable. Cardiac output decreased with increasing levelsof sustained positive airway pressure (P=0.001). The fall in SV for agiven airway pressure increased with increasing age (P=0.02). The mechanisms responsible for the increase of the magnitude of the fall in stroke volume with age remain to be elucidated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/05/20 alle ore 18:16:56