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Titolo:
ENDOTHELINS AND SARAFOTOXINS - RECEPTOR HETEROGENEITY
Autore:
SOKOLOVSKY M;
Indirizzi:
TEL AVIV UNIV,GEORGE S WISE FAC LIFE SCI,DEPT BIOCHEM,NEUROBIOCHEM LAB IL-69978 TEL AVIV ISRAEL
Titolo Testata:
International Journal of Biochemistry
fascicolo: 3, volume: 26, anno: 1994,
pagine: 335 - 340
SICI:
0020-711X(1994)26:3<335:EAS-RH>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-2-ADRENERGIC RECEPTOR; CLONING; CELLS; EXPRESSION; ANTAGONIST; SUBTYPES; TISSUES; FAMILY; HEART; BRAIN;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
M. Sokolovsky, "ENDOTHELINS AND SARAFOTOXINS - RECEPTOR HETEROGENEITY", International Journal of Biochemistry, 26(3), 1994, pp. 335-340

Abstract

1. Endothelins (ETs) and sarafotoxins (SRTXs) belong to a family of 21-amino-acid peptides comprising at least eight isoforms. 2. ET exertsmultiple pharmacological effects through its receptors. 3. This review summarizes the observations and findings pointing to the existence of receptor subtypes and leading to their identification. 4. Two receptor subtypes have been cloned and stably expressed. 5. The existence ofat least two more is predicted by dissimilar ligand potencies in different tissues, kinetics of receptor-ligand interactions, and cross-linking of receptors and radiolabeled ligands.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 04:19:15