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Titolo:
HYPOLIPEMIC AND ANTIATHEROSCLEROTIC EFFECTS OF ORAL GYMNEMA-SYLVESTRER BR LEAF EXTRACT IN ALBINO-RATS FED ON A HIGH-FAT DIET
Autore:
BISHAYEE A; CHATTERJEE M;
Indirizzi:
JADAVPUR UNIV,DEPT PHARMACEUT TECHNOL,DIV BIOCHEM CALCUTTA 700032 W BENGAL INDIA JADAVPUR UNIV,DEPT PHARMACEUT TECHNOL,DIV BIOCHEM CALCUTTA 700032 W BENGAL INDIA
Titolo Testata:
PTR. Phytotherapy research
fascicolo: 2, volume: 8, anno: 1994,
pagine: 118 - 120
SICI:
0951-418X(1994)8:2<118:HAAEOO>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPENDENT DIABETES-MELLITUS; CORONARY HEART-DISEASE; CHOLESTEROL; LEAVES;
Keywords:
GYMNEMA-SYLVESTRE; HYPOLIPEMIC AND ANTIHYPERCHOLESTERAEMIC ACTIVITY; ANTIATHEROGENIC INDEX;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
A. Bishayee e M. Chatterjee, "HYPOLIPEMIC AND ANTIATHEROSCLEROTIC EFFECTS OF ORAL GYMNEMA-SYLVESTRER BR LEAF EXTRACT IN ALBINO-RATS FED ON A HIGH-FAT DIET", PTR. Phytotherapy research, 8(2), 1994, pp. 118-120

Abstract

Gymnema sylvestre R. Br. leaf extract (25-100 mg/kg) when orally administered to experimentally induced hyperlipidaemic rats for 2 weeks, reduced the elevated serum triglyceride (TG), total cholesterol (TC), very low-density lipoprotein (VLDL)-and low-density lipoprotein (LDL)-cholesterol in a dose-dependent manner. The decreased serum high-density lipoprotein (HDL)-cholesterol and antiatherogenic index (AAI) in hyperlipidaemia were also reversed towards normalization. The ability of this extract (at 100 mg/kg) to lower TG and TC in serum and its antiatherosclerotic potential were almost similar to that of a standard lipid lowering agent-clofibrate.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 12:16:53