Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
COLLAGENASE, GELATINASE AND ELASTASE ACTIVITIES IN SULCULAR FLUID OF OSSEOINTEGRATED IMPLANTS AND NATURAL TEETH
Autore:
INGMAN T; KONONEN M; KONTTINEN YT; SIIRILA HS; SUOMALAINEN K; SORSA T;
Indirizzi:
UNIV HELSINKI,DEPT ANAT,POB 9,SILTAVUORENPENGER 20A SF-00014 HELSINKIFINLAND UNIV HELSINKI,DEPT PERIODONTOL SF-00014 HELSINKI FINLAND UNIV HELSINKI,DEPT PROSTHET DENT SF-00014 HELSINKI FINLAND UNIV HELSINKI,DEPT MED CHEM SF-00014 HELSINKI FINLAND UNIV HELSINKI,DEPT ANAT SF-00014 HELSINKI FINLAND
Titolo Testata:
Journal of clinical periodontology
fascicolo: 4, volume: 21, anno: 1994,
pagine: 301 - 307
SICI:
0303-6979(1994)21:4<301:CGAEAI>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN FIBROBLAST COLLAGENASE; GINGIVAL CREVICULAR FLUID; MATRIX METALLOPROTEINASES; INTERSTITIAL COLLAGENASES; TETRACYCLINE-INHIBITION; NEUTROPHIL PROTEINASES; LEUKOCYTE COLLAGENASE; PERIODONTAL-DISEASE; SECRETED FORMS; ADULT;
Keywords:
ELASTASE; COLLAGENASE; GELATINASE; OSSEOINTEGRATED IMPLANT; SULCULAR FLUID;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
T. Ingman et al., "COLLAGENASE, GELATINASE AND ELASTASE ACTIVITIES IN SULCULAR FLUID OF OSSEOINTEGRATED IMPLANTS AND NATURAL TEETH", Journal of clinical periodontology, 21(4), 1994, pp. 301-307

Abstract

Proteinases play a key role in the physiological degradation and remodelling of the periodontal tissues. The role of these enzymes in tissue remodelling in connection with the insertion of dental endosseous implants has not been elucidated. Therefore, the aim of the present study was to identify the eventual presence of collagenase, gelatinase andelastase activities in periimplant sulcus fluid (PISF) of osseointegrated implants. Gelatinolytic activity in the samples was studied with gelatin-zymograms. Collagenase activity and its susceptibility to tetracycline-inhibition were monitored with SDS-polyacrylamide gel electrophoresis and laser densitometry, and elastase activity with synthetic substrate. Low activities of elastase and collagenase were detected inboth PISF of osseointegrated implant patients and gingival crevicularfluid (GCF) of the control patients whereas significantly higher activities were detected in GCF of adult periodontitis patients. Also the profiles of gelatinases were similar in PISF of osseointegrated implant patients and GCF of the controls, but differed from the profile of active gelatinases present in GCF of adult periodontitis patients. The similar activities/characteristics of these proteinases in both periimplant sulcus fluid of healthy dental implants and GCF of healthy natural teeth suggest that they comprise the major proteinases for both periodontal and periimplant tissue remodelling or destruction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 05:42:54