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Titolo: CENTRAL MEDIATION OF TRACHEAL PRESSURE THROUGH H(1) AND H(2) RECEPTORS AFTER HISTAMINE ADMINISTRATION TO THE 4TH VENTRICLE OF ANESTHETIZED RABBIT
Autore: KANAMARU M; IWASE M; HOMMA I;
- Indirizzi:
- SHOWA UNIV,SCH MED,DEPT PHYSIOL,1-5-8 HATANODAI,SHINAGAWA KU TOKYO 142 JAPAN SHOWA UNIV,SCH MED,DEPT PHYSIOL,1-5-8 HATANODAI,SHINAGAWA KU TOKYO 142 JAPAN
- Titolo Testata:
- Neuroscience letters
fascicolo: 1-2,
volume: 169,
anno: 1994,
pagine: 35 - 38
- SICI:
- 0304-3940(1994)169:1-2<35:CMOTPT>2.0.ZU;2-9
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- INTRAVENTRICULAR-INJECTION; BRAIN; RAT; H1-RECEPTORS; SYSTEM; CAT;
- Keywords:
- ANESTHETIZED RABBIT; TRACHEAL PRESSURE; 4TH VENTRICLE; HISTAMINE; H(1) RECEPTOR; H(2) RECEPTOR; SYMPATHETIC NERVOUS SYSTEM;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Science Citation Index Expanded
- Citazioni:
- 23
- Recensione:
- Indirizzi per estratti:
-
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- Citazione:
- M. Kanamaru et al., "CENTRAL MEDIATION OF TRACHEAL PRESSURE THROUGH H(1) AND H(2) RECEPTORS AFTER HISTAMINE ADMINISTRATION TO THE 4TH VENTRICLE OF ANESTHETIZED RABBIT", Neuroscience letters, 169(1-2), 1994, pp. 35-38
Abstract
Administration of 1.5, 5.0 and 15 nmol histamine (HA) into the fourthventricle (IVth) decreased tracheal pressure (P(T) dose-dependently in anesthetized rabbits. Maximum decrease of P(T) occurred 0.9 +/- 0.1 min (mean +/- S.E.M., n = 9) after administration of 15 nmol, and recovery occurred at 4.5 +/- 1.0 min (n = 9). The decrease of P(T) was blocked by the H-1 receptor antagonist, pyrilamine administration into the IVth, or intravenous injection of the alpha-adrenoceptor antagonist,phentolamine. Recovery from the P(T) decrease was delayed by the H-2 receptor antagonist, cimetidine. The results suggest that HA centrallydecreases P(T) through H-1 receptors, which action is mediated by thesympathetic nervous system, and this decrease may be modulated through H-2 receptors.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 06:02:58