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Titolo:
CYTOCHEMICAL CHARACTERIZATION OF SULFOGLYCOCONJUGATES AND SIALOGLYCOCONJUGATES OF HUMAN LARYNGEAL GLANDULAR CELLS
Autore:
CASTELLS MT; MADRID JF; AVILES M; MARTINEZMENARGUEZ JA; BALLESTA J;
Indirizzi:
UNIV MURCIA,SCH MED,DEPT CELL BIOL,HISTOL & GEN EMBRYOL SECT E-30071 MURCIA SPAIN UNIV MURCIA,SCH MED,DEPT CELL BIOL,HISTOL & GEN EMBRYOL SECT E-30071 MURCIA SPAIN UNIV PAIS VASCO,SCH MED & DENT,DEPT CELL BIOL & MORPHOL SCI VIZCAYA SPAIN
Titolo Testata:
The Journal of histochemistry and cytochemistry
fascicolo: 4, volume: 42, anno: 1994,
pagine: 485 - 496
SICI:
0022-1554(1994)42:4<485:CCOSAS>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ASPARAGINE-LINKED OLIGOSACCHARIDES; CARBOHYDRATE CYTO-CHEMISTRY; DATURA-STRAMONIUM LECTIN; MUCIN-TYPE GLYCOPROTEINS; WHEAT-GERM-AGGLUTININ; GOLD COMPLEXES; HISTOCHEMICAL-DEMONSTRATION; ELECTRON-MICROSCOPY; LIGHT-MICROSCOPY; O-GLYCOSYLATION;
Keywords:
HUMAN LARYNGEAL GLANDS; SULFOGLYCOCONJUGATES; SIALOGLYCOCONJUGATES; CYTOCHEMISTRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
M.T. Castells et al., "CYTOCHEMICAL CHARACTERIZATION OF SULFOGLYCOCONJUGATES AND SIALOGLYCOCONJUGATES OF HUMAN LARYNGEAL GLANDULAR CELLS", The Journal of histochemistry and cytochemistry, 42(4), 1994, pp. 485-496

Abstract

The composition and distribution of sulfo- and sialoglycoconjugates in human laryngeal glands have been investigated at light and electron microscopic levels by use of peroxidase-, digoxigenin-, and colloidal gold-conjugated lectins in combination with several chemical and enzymatic deglycosylation procedures. The present study reveals a variety of terminal oligosaccharide sequences in serous and mucous glands. Serous cells contained glycoconjugates with terminal Neu5Ac (alpha 2-3) Gal (beta 1-4) GlcNAc, Neu5Ac (alpha 2-6) Gal/GalNAc, Neu5Ac (alpha 2-3/6) Gal (beta 1-3 GalNAc, GlcNAc, and Gal (beta 1-4) GlcNAc sequences. Scarce SO(4)Gal(beta 1-3)GalNAc terminal oligosaccharide chains mere detected. Serous cells show wide morphological variability of secretorygranules (electron lucent, electron dense, and bizonal) with different lectin affinities. Glycoconjugates in human laryngeal mucous glands contained a variety of terminal oligosaccharide sequences including SO(4)Gal(beta 1-4)GlcNAc, SO(4)Gal(beta 1-3) GalNAc, SO(4)GalNAc, and Neu5Ac(alpha 2-3)GalNAc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 23:44:41