Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ADVERSE EARLY EXPERIENCES AFFECT NORADRENERGIC AND SEROTONERGIC FUNCTIONING IN ADULT PRIMATES
Autore:
ROSENBLUM LA; COPLAN JD; FRIEDMAN S; BASSOFF T; GORMAN JM; ANDREWS MW;
Indirizzi:
UNIV HOSP BROOKLYN,ROOM 373,445 LEROY RD BROOKLYN NY 11203 SUNY HLTH SCI CTR,DEPT PSYCHIAT BROOKLYN NY 11203 SUNY HLTH SCI CTR,PRIMATE BEHAV LAB BROOKLYN NY 00000 COLUMBIA UNIV,COLL PHYSICIANS & SURGEONS,DEPT PSYCHIAT NEW YORK NY 00000
Titolo Testata:
Biological psychiatry
fascicolo: 4, volume: 35, anno: 1994,
pagine: 221 - 227
SICI:
0006-3223(1994)35:4<221:AEEANA>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PANIC DISORDER; RHESUS-MONKEYS; BEHAVIORAL-INHIBITION; NONHUMAN-PRIMATES; HEALTHY-SUBJECTS; ORAL YOHIMBINE; META-CPP; ANXIETY; IMIPRAMINE; CHILDREN;
Keywords:
PANIC; YOHIMBINE; MCPP; ANXIETY; PRIMATES DEVELOPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
L.A. Rosenblum et al., "ADVERSE EARLY EXPERIENCES AFFECT NORADRENERGIC AND SEROTONERGIC FUNCTIONING IN ADULT PRIMATES", Biological psychiatry, 35(4), 1994, pp. 221-227

Abstract

It has been proposed that certain adverse early experiences may play a role in determining subsequent susceptibility to adult anxiety and affective disorders and this relationship may be the result of altered neurodevelopment of the noradrenergic and/or serotonergic systems. In this study of nonhuman primates, the predictability of foraging requirements for mothers during an early period of their infants' lives was manipulated. When the offspring were young adults, these early manipulations were related to differences in behavioral response to acute administration of two putative anxiety-provoking agents: the noradrenergic probe, yohimbine, and the serotonergic probe, mCPP. These long-term effects of the developmental environment on subsequent pharmacologicalresponsivity suggest that both neuronal systems may be permanently altered by early experiential factors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 05:15:04