Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
GLYCOSPHINGOLIPID COMPONENT PROFILES OF HUMAN GLIOMAS CORRELATE WITH HISTOLOGICAL TUMOR TYPES - ANALYSIS OF INTERINDIVIDUAL AND TUMOR-REGIONAL DISTRIBUTION
Autore:
JENNEMANN R; MENNEL HD; BAUER BL; WIEGANDT H;
Indirizzi:
PHILIPPS UNIV,INST PHYSIOL CHEM D-35043 MARBURG GERMANY PHILIPPS UNIV,INST PHYSIOL CHEM D-35043 MARBURG GERMANY UNIV MARBURG,ZENTRUM PATHOL,NEUROPATHOL ABT W-3550 MARBURG GERMANY UNIV MARBURG,ZENTRUM OPERAT MED,NEUROCHIRURG ABT W-3550 MARBURG GERMANY
Titolo Testata:
Acta neurochirurgica
fascicolo: 2-4, volume: 126, anno: 1994,
pagine: 170 - 178
SICI:
0001-6268(1994)126:2-4<170:GCPOHG>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
GANGLIOSIDES;
Keywords:
GLIOMAS; GLYCOSPHINGOLIPIDS; GANGLIOSIDES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
R. Jennemann et al., "GLYCOSPHINGOLIPID COMPONENT PROFILES OF HUMAN GLIOMAS CORRELATE WITH HISTOLOGICAL TUMOR TYPES - ANALYSIS OF INTERINDIVIDUAL AND TUMOR-REGIONAL DISTRIBUTION", Acta neurochirurgica, 126(2-4), 1994, pp. 170-178

Abstract

Three types of glycosphingolipid (GSL) component profiles have been established for human intracranial gliomas. GSL-type I shows only G(lac)- and lacto-series-sialoglycolipids. Type II consist of G(lac)and G(tri)-gangliosides, whereas only GSL-type III contains sulphatide and, as a major neutral glycolipid, galactocerebroside, besides gangliosidesof the G(lac)-, G(tri)-, G(tet)-families. Whole gliomas of malignancygrading I/II, III and IV, display GSL-Types III, II, and I, respectively. Thus, the GSL component distribution of the samples taken after surgery from three individual gliomas and two biopsies correlate closely with the general diagnosis of these tumours. Arthrobacter ureafaciens sialidase was used for the characterization of gangliosides. GSL-type analysis of multiple regional samples, taken from necropsy and biopsy, were determined by microanalysis of microscopic cryostat section, and shown to be in good agreement with their histology. The results validate the relevance of tumour ganglioside analysis for the characterization and diagnosis of gliomas.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 17:21:46