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Titolo:
INVOLVEMENT OF CANINE ORAL PAPILLOMAVIRUS IN GENERALIZED ORAL AND CUTANEOUS VERRUCOSIS IN A CHINESE SHAR-PEI DOG
Autore:
SUNDBERG JP; SMITH EK; HERRON AJ; JENSON AB; BURK RD; VANRANST M;
Indirizzi:
ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL,ULLMANN BLDG,ROOM 515,1300 MORRIS PK AVE BRONX NY 10461 ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL BRONX NY 10461 JACKSON LAB BAR HARBOR ME 00000 ANIM HOSP LAKE,ANIM DERMATOL CLIN W PALM BEACH FL 00000 UNIV MIAMI,SCH MED,DEPT PATHOL MIAMI FL 00000 GEORGETOWN UNIV,SCH MED,DEPT PATHOL WASHINGTON DC 00000
Titolo Testata:
Veterinary pathology
fascicolo: 2, volume: 31, anno: 1994,
pagine: 183 - 187
SICI:
0300-9858(1994)31:2<183:IOCOPI>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; RENAL-ALLOGRAFT RECIPIENTS; IGA DEFICIENCY; HPV TYPES; DNA; INFECTION; LESIONS; WOMEN; SKIN; IMMUNOSUPPRESSION;
Keywords:
PAPILLOMAVIRUS; SKIN; IMMUNOSUPPRESSION; STEROIDS; ORAL CAVITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
J.P. Sundberg et al., "INVOLVEMENT OF CANINE ORAL PAPILLOMAVIRUS IN GENERALIZED ORAL AND CUTANEOUS VERRUCOSIS IN A CHINESE SHAR-PEI DOG", Veterinary pathology, 31(2), 1994, pp. 183-187

Abstract

Severe papillomatosis developed in the oral cavity and spread throughout the haired skin of the trunk and limbs of an 8-month-old female Chinese Shar Pei dog. The dog had received corticosteroids prior to referral, which was associated with the onset of demodecosis and papillomatosis. Papillomavirus structural antigens were detected in biopsies byimmunohistochemistry using a panel of monoclonal and polyclonal antibodies. An 8.2-kilobase papillomavirus-specific DNA molecule was detected in the cutaneous lesions by high stringency Southern blot hybridization using a cloned canine oral papillomavirus DNA probe. Restriction enzyme analysis revealed that the virus in the cutaneous lesions was identical to the canine oral papillomavirus. Discontinuation of the steroids combined with the use of a mitocide, antibiotics, and an autogenous vaccine resolved the demodecosis and papillomatosis. This case report suggests that corticosteroid-induced immunosuppression can expand the tissue tropism of papillomaviruses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:46:14