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Titolo:
THE INCIDENCE OF 2ND NEOPLASMS IN ADVANCE D LARYNGEAL-CANCER - IMPACTON SURVIVAL
Autore:
ROVIROSA A; BELLMUNT J; LOPEZ A; FERNANDEZ M; GUERRA M; MONTAGUT J;
Indirizzi:
GUIPUZCON 92,3 1A ESC IZQDA E-08020 BARCELONA SPAIN UNIV AUTONOMA BARCELONA,SERV RADIOTERAPIA BARCELONA SPAIN UNIV AUTONOMA BARCELONA,SERV ONCOL BARCELONA SPAIN UNIV AUTONOMA BARCELONA,HEMATOL CLIN BARCELONA SPAIN
Titolo Testata:
Medicina Clinica
fascicolo: 4, volume: 102, anno: 1994,
pagine: 121 - 124
SICI:
0025-7753(1994)102:4<121:TIO2NI>2.0.ZU;2-P
Fonte:
ISI
Lingua:
SPA
Soggetto:
SQUAMOUS-CELL CARCINOMA; MULTIPLE PRIMARY TUMORS; MALIGNANT-TUMORS; NECK-CANCER; HEAD; PREVENTION; TRACT; LUNG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
A. Rovirosa et al., "THE INCIDENCE OF 2ND NEOPLASMS IN ADVANCE D LARYNGEAL-CANCER - IMPACTON SURVIVAL", Medicina Clinica, 102(4), 1994, pp. 121-124

Abstract

BACKGROUND: The incidence of second neoplasms in laryngeal cancer is greater than that of other neoplasms. The appearance of a second neoplasm in these patients represents an important decrease in survival. The prevalence of second neoplasms in laryngeal cancer and its impact onsurvival was determined in this study. METHODS: Seventy-eight patients with advanced laryngeal cancer (stages III and IV of the UICC) who had been treated with erradicative surgery from January 1984 to December 1988; and who were attended in the Radiotherapy and Oncology Department of the Ciutat Sanitaria i Universitaria Vall d'Hebron were retrospectively studied. All were postoperatively submitted to radiotherapy. RESULTS: Ten of the 78 patients studied (13 %) developed a second neoplasm. The most frequent localization was pulmonary (70 %). In 9 of the10 patients the appearance of the second neoplasm was considered metachronic with 60 % being detected within the first 24 months after the diagnosis of the laryngeal neoplasm. The survival of the whole group was 80 % at 2 years and 51 % at 5 years. Survival of the patients with the second neoplasm was lower: 71 % at 2 years and 5 % at 5 years (p <0.0001). CONCLUSIONS: The presence of a second neoplasm in patients with laryngeal cancer is high. The survival of patients with advanced laryngeal cancer who develop a second neoplasm is significantly lower than that of other patients with this neoplasm.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/10/20 alle ore 08:53:25