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Titolo:
SYNERGIST INTERACTION BETWEEN ANGIOTENSIN-II AND DOCA ON SODIUM AND WATER-BALANCE IN RATS
Autore:
CAMARGO LAD; SAAD WA; DELUCA LA; RENZI A; SILVEIRA JEN; MENANI JV;
Indirizzi:
UNESP,PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,1680 HUMAITA ST,POB 331 BR-14801903 ARARAQUARA SP BRAZIL UNESP,PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL BR-14801903 ARARAQUARA SP BRAZIL
Titolo Testata:
Physiology & behavior
fascicolo: 3, volume: 55, anno: 1994,
pagine: 423 - 427
SICI:
0031-9384(1994)55:3<423:SIBAAD>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACEREBROVENTRICULAR INFUSION; APPETITE; EXCRETION; SALT; MINERALOCORTICOIDS; INTERFERENCE; DRINKING;
Keywords:
ANGIOTENSIN II; DOCA; WATER INGESTION; SALT INGESTION; URINE EXCRETION; SODIUM EXCRETION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
L.A.D. Camargo et al., "SYNERGIST INTERACTION BETWEEN ANGIOTENSIN-II AND DOCA ON SODIUM AND WATER-BALANCE IN RATS", Physiology & behavior, 55(3), 1994, pp. 423-427

Abstract

Blockade of central angiotensin receptors with the specific antagonist [Leu(8)]-ANG II abolished water ingestion and water and sodium excretion induced by infusion of angiotensin II (ANGII) into the lateral ventricle (LV) of rats. The antagonist reduced but did not suppress the salt appetite induced by ANGII infusion. Subcutaneous injection of deoxycorticosterone acetate (DOCA) caused increases in water and 3% NaCl ingestion and decreases in sodium excretion. When central ANGII infusion was combined with peripheral DOCA, the water intake was similar to that induced by ANGII alone and the ingestion of 3% NaCl was increased, whereas sodium excretion was inhibited. When ANGII was infused alone, a detailed temporal analysis of fluid and sodium balance showed a negative balance similar those saline controls that persisted throughoutthe experiment. Combined administration of ANGII and DOCA induce significant changes in water and sodium balance. Sodium and water maintained a positive balance through out the 8-h experiment. The data supportan interaction of central ANGII and DOCA on sodium intake and water and sodium balance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:52:36